摘要
目的探讨肠内营养应用于重症急性胰腺炎患者的疗效及改善营养状况的效果。方法采用随机平行对照法将2013年1月—2016年2月期间89例重症急性胰腺炎患者进行分组,对照组44例给予全胃肠外营养支持,观察组45例给予肠内营养支持,对比两组患者治疗后临床症状恢复时间、住院时间,与血清白蛋白、前白蛋白、血清淀粉酶、体质量改善效果,及并发症发生率。计数资料比较采用χ2检验,计量资料比较采用t检验,P<0.05认为差异具有统计学意义。结果观察组腹胀缓解时间、体温恢复时间、血尿淀粉酶恢复时间及住院时间[(5.59±2.03)d、(11.33±2.46)d、(15.93±2.61)d、(36.92±12.66)d],均低于对照组[(1.98±1.39)d、(7.49±1.82)d、(9.98±2.33)d、(19.93±7.11)d](均P<0.05);观察组治疗后血清白蛋白及前白蛋白高于对照组,血清淀粉酶低于对照组(均P<0.05);观察组体质量略高于对照组(P>0.05);观察组并发症发生率、死亡率(15.56%、0%)均低于对照组(59.09%、11.36%)(均P<0.05)。结论肠内营养能够显著改善重症急性胰腺炎患者的营养状况,缓解临床症状,提高生存率,安全性高,值得临床的推广及应用。
Objective To discuss the effect of enteral nutrition on patients with severe acute pancreatitis（SAP） and to improve the nutritional status. Methods A total of 89 cases with severe acute pancreatitis selected from January 2015 to February 2016 were randomly divided into two groups, 44 cases in the control group and 45 cases in the observation group. Patients in the control group were given total parenteral nutrition, while the observation group were given enteral nutrition support. Clinical symptom recovery time and hospitalization time were compared between two groups after treatment, as well as the improvement of serum albumin, prealbumin, serum amylase, body mass, and the incidence of complications. Measurement data uses t test and count data uses χ2 test. P〈0.05 is considered statistically significant. Results In the observation group, remission time of abdominal distention, recovery time of body temperature, urine amylase recovery time and hospitalization time [（5.59±2.03） d,（11.33±2.46）d,（15.93±2.61） d,（36.92±12.66） d] were significantly lower than the control group [（1.98±1.39） d,（7.49±1.82）d,（9.98±2.33） d,（19.93±7.11） d]（all P〈0.05）. Compared to the control group, levels of serum albumin and prealbumin were significantly higher and level of serum amylase was significantly lower in the observation group（all P〈0.05）. Body quality of the patients in observation group is higher than that in the control group（P〈0.05）. The complication rate（15.56%） and mortality rate（0%） were significantly lower compared to the control group（P〈0.05）. Conclusion Enteral nutrition can significantly improve the nutritional status of patients with severe acute pancreatitis, alleviate clinical symptoms and improve survival rate. Therefore, it is worthy of clinical application.
出处
《社区医学杂志》
2017年第15期7-9,共3页
Journal Of Community Medicine
关键词
重症急性胰腺炎
肠内营养
疗效
营养状况
Severe acute pancreatitis
Enteral nutrition
Curative effect
Nutritional status
