摘要
目的:观察阿奇霉素结合中医综合疗法治疗小儿支气管肺炎的临床效果。方法:选取90例支气管肺炎住院患儿,按随机数字表法分为A组、B组与C组,各30例,三组均给予阿奇霉素序贯疗法治疗,在此基础上,A组增加中药内服疗法,即口服小儿咳喘灵口服液,B组增加中药外敷疗法,即外敷神阙贴,C组则中药内服小儿咳喘灵口服液加中药外敷疗法,三组治疗观察时间均为7 d,治疗前后,以血清降钙素原(PCT)、血清白细胞介素-6(IL-6)及超敏C反应蛋白(hs-CRP)、治疗有效率、临床症状消失时间、以及住院时间等指标评定三组临床效果。结果:C组IL-6、hs-CRP、PCT评分均明显低于A组与B组,差异有显著统计学意义(P<0.01)。A组与B组比较,IL-6、hs-CRP、PCT评分差异无统计学意义(P>0.05)。C组各项临床症状消退时间均明显少于A组与B组,差异有显著统计学意义(P<0.01),A组与B组临床症状消退时间及住院时间比较,差异无统计学意义(P>0.05)。A组治疗总有效率86%,B组82%,C组97%,C组总有效率明显高于A组与B组,差异有统计学意义(P<0.05),A组与B组治疗有效率比较,差异无统计学意义(P>0.05)。结论:阿奇霉素结合中医综合疗法治疗小儿支气管肺炎,可取得良好的临床治疗效果。
Objective To investigate clinical effectsof Azithromycin combined with traditional Chinese medicine combined therapy in treatment of bronchopneumonia in children. Methods ： 90 cases of hospitalized children with bronchopneumonia were ran-domly divided into were divided into A group, B group and C group, 30 cases in each group. The three groups were given Azithromycin sequential therapy. Besides, A group was givenoral medicinal herbs therapy （Xiaoerkechuanning oral liquid） , B group used external application ofChinese medicinal herbs （external shenquetie） , while C group received the Xiaoerkechuanning oral liquid and external application of Chinese medicinal herbs. The observation time was 7d. The levels of serum procalcitonin （ PCT） , interleukin -6 （IL- 6） and high sensitive C reactive protein （hs-CRP）before and after the treatment were detected. The clinical effects of the three groups were evaluated by the treatment effective rate, clinical symptomdisappearance timeand hospitalization time. Results： The scores of IL - 6, hs-CRP and PCT in C group were significantly lower than those in A group and Bgroup, and the differences were statistically signif-icant （P〈0. 01）. There were no significant differences in IL-6, hs-CRP and PCT scores between A group and B group （ P〉0.05）. The clinical symptomdisappearance time in C group was significantly less than those in A group and Bgroup, and the differences were statistically significant （ P〈0. 01）. There was no significant difference in clinical symptomdisappearance time between A group and B group （P〉0.05）. The total effective rates of A group, B group and C group were 86%, 82% and 97% , separately; the differences between C group and A group as well as between C group and B group were statistically significant （P〈0.05）; however, the difference between A group and B group was not statistically significant（ P〉0.05）. Conclusions ： Azithromycin combined with traditional Chinese medicine combined therapy in the treatment of bronchopneumonia in children can achieve good clinical effects.
出处
《中国民康医学》
2017年第12期50-52,共3页
Medical Journal of Chinese People’s Health
关键词
阿奇霉素
中医综合疗法
小儿支气管肺炎
Azithromycin
Chinese medicine combined therapy
Children bronchopneumonia
