摘要
目的探讨尿动力学检查在间质性膀胱炎/膀胱疼痛综合征(IC/BPS)患者的诊断及症状严重程度评估中的应用价值。方法回顾性分析2009年11月至2016年3月收治的71例IC/BPS患者的临床资料,其中男12例,女59例,年龄20~76岁,平均(43±14)岁;病程6~240个月,平均(62±37)个月。所有患者先采用O'Leary-Sant调查表进行症状评估,再行尿动力学检查,最后在麻醉下行膀胱镜检和水扩张。分析尿动力学检查结果与症状严重程度(ICSI、ICPI评分)、膀胱镜下黏膜改变、麻醉下最大膀胱容量之间的关系。结果 ICSI、ICPI评分高的患者膀胱初感觉容量、初始尿意容量、强烈尿意容量和尿流量较ICSI、ICPI评分低的患者小(P<0.05);膀胱镜下黏膜改变不同分级患者间膀胱初感觉容量、初始尿意容量、强烈尿意容量和尿流量差异具有统计学意义(P<0.05);膀胱初感觉容量、初始尿意容量、强烈尿意容量、尿流量和最大尿流率与麻醉下膀胱最大容量呈正相关(r分别为0.462、0.391、0.414、0.616、0.237,P<0.05)。结论尿动力学检查能够为IC/BPS患者的诊断和症状严重程度评估提供有效的客观依据,具有重要的临床应用价值。
Objective To investigate the correlation between symptom severity, urodynamic testing（UDT）, and cystoscopy result in interstitial cystitis/painful bladder syndrome patients. MethodsDuring November 2009 to March 2016, 71 IC/BPS patients were treated, including 59 women and 12 men, with mean age of（43±14） years and mean course of the disease of（62±37） months. O＇LearySant questionnaire was used for IC/BPS symptom assessment, and urodynamic testing and cystoscopic hydrodistention were performed subsequently. The relationship between symptom severity, urodynamic testing and cystoscopy was evaluated. Result The mean volumes at first sensation of filling（FSF）, first desire to void（FD）, strong desire to void（SD） and voided volume（VV） were inversely correlated with ICSI and ICPI（all P〈0.05）, Significantly lower mean volumes for FSF, FD, SD and VV were found in patients with higher grade of classification under cystoscopy,（all P〈0.05）, The anaesthetic maximal bladder capacity（MBC） was positively correlated with FSF, FD, SD, Qmax and VV（r=0.462, 0.391, 0.414, 0.616, 0.237 respectively, all P〈0.05）. Conclusion Urodynamic testing may be a useful test in the diagnosis and symptom assessment in IC/BPS patients.
作者
李文标
谢俊聪
杨飞
李腾成
吴珍
刘柏隆
湛海伦
周祥福
Li Wenbiao Xie Juncong Yang Fei Li Tengcheng Wu Zhen Liu Bolong Zhan Hailun Zhou Xiangfu(Department of Urology, the Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510630, China)
出处
《中华腔镜泌尿外科杂志（电子版）》
2017年第4期49-52,共4页
Chinese Journal of Endourology(Electronic Edition)
基金
国家自然科学基金(81670688)
广东省自然科学基金(2016A030313192)
广东省医学科学技术研究基金项目(A2017365)
关键词
间质性膀胱炎
尿动力学
诊断
症状评估
Interstitial cystitis
Urodynamic
Diagnosis
Symptoms assessment
