摘要
To exploring the effect of Allitridi on anti arrhythmia, cardiac electrophysiological characteristic are detected in guinea pig atrium muscles by intracellular microelectrode technique. Result:The automaticity which adrenalin induces is inhibited at 125 and 625 umol/L. The force of contraction is weakened; the intensity time curve which reflects excitability move towards right after 625 umol/L administration. under 25、125、625 μmol/L, functional refractory period、action potential duration of 50% and 90% repolarization、 sinus cycle longness are extended, a relationship between dose and effect exist at SCL. Conclusion: Automaticity、 excitability and refractoriness not only are inhibited but also action potential durations are extended after Allitridi administration.
To exploring the effect of Allitridi on anti arrhythmia, cardiac electrophysiological characteristic are detected in guinea pig atrium muscles by intracellular microelectrode technique. Result:The automaticity which adrenalin induces is inhibited at 125 and 625 umol/L. The force of contraction is weakened; the intensity time curve which reflects excitability move towards right after 625 umol/L administration. under 25、125、625 μmol/L, functional refractory period、action potential duration of 50% and 90% repolarization、 sinus cycle longness are extended, a relationship between dose and effect exist at SCL. Conclusion: Automaticity、 excitability and refractoriness not only are inhibited but also action potential durations are extended after Allitridi administration.
出处
《中国中医基础医学杂志》
CAS
CSCD
2002年第7期35-37,共3页
JOURNAL OF BASIC CHINESE MEDICINE
基金
湖北省教委基金资助项目 (No .940 3 1)
