摘要
目的:探讨食管癌术后患者的中医体质类型分布及其预后因素。方法:采用标准化的中医体质分类量表,对229例食管癌术后患者进行中医体质评估,并分析中医体质类型等因素对食管癌术后预后的影响。结论:患者的体质类型分布为:平和质45例(19.7%)、气虚质57例(24.9%)、阳虚质48例(20.9%)、阴虚质15例(6.6%)、痰湿质7例(3.0%)、湿热质5例(2.2%)、血瘀质39例(17.0%)、气郁质11例(4.9%)、特禀质2例(0.8%)。单因素分析表明中医体质(平和质、血瘀质、阳虚质、气虚质)、年龄、TNM、肿瘤大小、N分期、并发症是食管癌术后的预后相关因素。Cox多因素分析表明中医体质(平和质、血瘀质、阳虚质、气虚质)、TNM、N分期是食管癌术后独立的预后因素;气虚质是影响食管癌的强独立危险因素。结果:食管癌术后的偏颇体质主要以气虚质、阳虚质、瘀血质为主,气虚质是影响食管癌术后的强独立危险因素。
Objective: To discuss the distribution of TCM constitution and analyze the prognostic factors a- mong cases with the Esophageal carcinoma. Methods: The standardized classification measurement questionnaire of nine constitution Chinese medicine was used to investigate the Chinese medicine constitution of 229 patients with esophageal carcinoma. The impacts of TCM constitution and other factors for prognosis of esophageal carcinoma were analyzed. Results: The types of Chinese medicine constitutions were as follows: gentleness, qi-deficiency, yang-deficiency, yin-deficiency, andphlegm-wetness, wet-heat, blood-stasis, qi-depression, special diathesis, the number of corresponding patients per constitution were asfollows: 45 (19.7%), 57 (2g.9%), 48 (20.9%), 15 (6.6%), 7 (3.0%), 5 (2.2%), 39 (17.0%), 11 (4.9%), 2 (0.8%) respectively. Single factor analysis showed that the traditional Chinese medicine physique (gentleness, blood-stasis, yang-deficiency, qi-deficiency), age, TNM, tumor size, N stage, complicationsis were prognostic factors after esophagectomy. Cox Multiple factors analysis showed that the traditional Chinese medicine physique (gentleness, blood-stasis, yang-deficiency, qi-deficiency), TNM, N stage were independent prognostic factors after esophagectomy, and that qi-deficien-cy type was an im- portant independent factor that might be worth further investigation for predicting prognosis. Conclusion: The constitutions of Chinese medicine in patients with sophageal carcinoma were predominantly gentleness, qi-deficiency, yang-deficiency, and blood-stasis types. Qi-deficiency type was a strong independent risk factor for esophageal cancer survival of sophageal carcinoma patients.
出处
《中医药导报》
2017年第16期58-60,共3页
Guiding Journal of Traditional Chinese Medicine and Pharmacy
关键词
食管癌
中医体质类型
预后因素
危险因素
esophageal carcinoma
TCM constitution
prognostic factors
risk factors