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活血化浊汤联合依达拉奉治疗气滞血瘀脑梗死随机平行对照研究 被引量:8

Randomized Parallel Controlled Study on the Treatment of Qi Stagnation and Blood Stasis in Cerebral Infarction by Activating Blood Circulation and Resolving Turbidity Decoction
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摘要 [目的]观察活血化浊汤联合依达拉奉治疗脑梗死疗效。[方法]使用随机平行对照方法,将95例住院患者按病志号抽签方法简单随机分为两组。对照组47例依达拉奉,30mg/次,1次/d,口服。治疗组48例活血化浊汤,水煎400mL,1剂/d,早晚分服;依达拉奉治疗同对照组。连续治疗1个月为1疗程。观测临床症状、日常生活能力评定(ADL)、神经功能缺损评分(NIHSS)、不良反应。治疗1疗程(1个月)。[结果]治疗组临床痊愈19例,显效16例,有效8例,无效5例,总有效率89.59%;对照组临床痊愈15例,显效13例,有效6例,无效13例,总有效率72.34%;治疗组疗效优于对照组(P<0.05)。NIHSS评分、ADL评分两组均有改善(P<0.01),治疗组改善优于对照组(P<0.01)。[结论]活血化浊汤联合依达拉奉治疗脑梗死,疗效满意,无严重不良反应,值得推广。 [Objective] To observe the therapeutic effect of Huoxue Huazhuo decoction combined with edaravone on cerebral infarction. [Method] 95 patients were randomly divided into two groups according to the random number method. The control group of 47 cases of edaravone, 30 mg/times, 1 time/d, oral. In the treatment group, 48 cases were treated with Huoxue Huazhuo decoction, 400 mL, 1 Ji/d, and then served in the morning and evening, and edaravone treatment was compared with the control group continuous treatment for 1 months for a course of 1. The clinical symptoms, daily living ability(ADL), neurological deficit score(NIHSS), adverse reactions were observed. 1 courses of treatment(1 months), 19 cases were cured after treatment in the treatment group. [Result] 16 cases were markedly effective, 8 cases effective, 5 cases ineffective, the total efficiency of 89.59%; control group 15 cases were cured clinically, 13 cases were markedly effective, 6 cases effective, 13 cases ineffective, the total efficiency of 72.34%; the treatment group is better than the the control group(P〈0.05). NIHSS score, ADL score of two groups were improved(P〈0.01), the treatment group was better than the control group(P〈0.01). [Conclusion] the treatment of cerebral infarction with Huoxue Hauzhuo decoction combined with edaravone has satisfactory curative effect and no serious adverse reactions.
出处 《实用中医内科杂志》 2017年第8期34-36,共3页 Journal of Practical Traditional Chinese Internal Medicine
关键词 脑梗死 气滞血瘀 活血化浊汤 依达拉奉 日常生活能力评定(ADL) 神经功能缺损评分(NIHSS) 中西医结合治疗 随机平行对照研究 cerebral infarction Qi stagnation and blood stasis activating blood circulation and resolving turbid decoction edaravone daily living ability assessment(ADL) neurological deficit score(NIHSS) combination of traditional Chinese and western medicine randomized controlled study
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