摘要
目的 研究并探讨急性口服药物中毒患者应用生理盐水洗胃的临床效果。方法 于2014年1月-2017年1月期间,选取本院急诊科收治的100例急性口服药物中毒患者作为研究对象,采取计算机随机数字分组法分为对照组、观察组,每组50例,对照组采用清水洗胃,观察组采用生理盐水洗胃,比较2组患者的抢救成功率、血清钠浓度、平均动脉压、并发症发生率。结果 观察组的抢救成功率明显高于对照组（P〈0.05）;洗胃后,观察组的血清钠浓度、平均动脉压未出现明显波动,而对照组的血清钠浓度、平均动脉压均低于洗胃前（P〈0.05）;观察组的并发症发生率明显低于对照组（P〈0.05）。结论 采用生理盐水对急性口服药物中毒患者进行洗胃,可有效提高其抢救成功率,减少并发症,还可避免其水电解质紊乱。
Objective To study and explore the clinical effect of saline lavage on patients with acute oral poisoning. Methods From January 2014 to January 2017, 100 cases of patients with acute oral drug poisoning who admitted in the emergency department of our hospital were selected as the research object, the patients were randomly divided into the control group and the observation group by taking digital computer random grouping method, 50 cases in each group, the control group used clean water to lavage, the observation group used saline to gastric lavage, the success rate of rescue, serum sodium concentration, mean arterial pressure and complication rate were compared between two groups. Results The success rate of rescur in the observation group was significantly higher than the control group （P〈0.05）; after gastric lavage, serum sodium concentration and mean arterial pressure in the observation group had not appear obvious fluctuation, and serum sodium concentration and mean arterial blood pressure in the control group were lower than those before gastric lavage （P〈0.05）; the incidence of complications in the observation group was significantly lower than that the control group （P〈0.05）. Conclusion The use of physiological saline for acute oral poisoning patients with gastric lavage, can effectively improve the success rate of rescue, reduce complications, but also to avoid water and electrolyte disorders.
出处
《中国生化药物杂志》
CAS
2017年第8期340-341,共2页
Chinese Journal of Biochemical Pharmaceutics
关键词
急性口服药物中毒
生理盐水
洗胃
acute oral poisoning
physiological saline
gastric lavage
