摘要
本文对50例充血性心力衰竭(下简称心衰)者以盲法用小量维生索C(Vit C)与1,6一二磷酸果糖(FDP)进行比较,观察临床及超声心动图测定的心功能改变。结果显示,两药治疗后临床疗效及心功能指标均无明显的改变,P均>0.05,组间比较亦无明显差异.P均>0.05.故FDP治疗充血性心衰的确切疗效尚难以确定。
Echocardiographic and clinical effects of fructose 1, 6—diphosphate (FDP) were studied in 50 patients with congestive heart failure. The patients were randomized into FDP and vitamin C (vit. C)group. In a blind study design, 5. 0g of FDP or 1.0g of vit. C was injected intravenously twice daily for five days. M mode echocardiographic assessment of loft ventricular function and clinical evidence of congestive heart failure were evaluated before and after treatment. The results showed that there wore no significant differences before and after treatment in both groups (P>0. 05) and also between two groups (P>0. 05).
This study indicates that FDP is not effective in improving cardiac function in patients with congestive heart failure.
出处
《中国循环杂志》
CSCD
1991年第6期553-555,共3页
Chinese Circulation Journal
关键词
心力衰竭
二磷酸果糖
充血性
Congestive heart failure
Fructose 1,6— diphosphate
