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冠心病患者血清载脂蛋白与脂质水平及临床意义 被引量:14

CLINICAL SIGNIFICANCE OF SERUM APOLIPOPROTEINS AND LIPIDS IN PATIENTS WITH CORONARY HEART DISEASE
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摘要 本文对307例冠状动脉造影患者的血清载脂蛋白A I、B及脂质(TC、HDL—C、TG)水平进行了分析。造影分冠状动脉病变组与冠状动脉正常组,所测指标在两组间均有非常显著差别(P【0.01—0.001)。ApoA I/Apo B比值判别冠状动脉存在有临床意义病变的敏感性及特异性优于其它所测指标。 Serum apolipoprotitn A-I(Apo A-I) and B(Apo B), total cholesterol (TC), high density lipoprotein-cholesterol (HDL-C) and triglyceride were determined in 307 patients undersoing coronary arteriography. There were significant differences in the serum levels of all lipids, apollpoprotiens as well as Apo A-I/Apo B and TC-HDL-C/HDL-C(P<0.01-0.001)among patients with and without angiographically defined coronary heart disease (CHD). Apo A-I/Apo B was the best one for discriminating CHD in all the measured parameters. At the reference limit of Apo A-I/Apo B of 1.30, the sensitivity and specificity for discriminating CHD was 72% and 70% respectively. Serum Apo A-I and B are better criteria than serum lipids in discriminating CHD.
作者 陆宗良 李芬
出处 《中国循环杂志》 CSCD 1991年第6期544-546,685-686,共3页 Chinese Circulation Journal
关键词 冠心病 载脂蛋白 胆固醇 Coronary heart disease Apolipoprotein Cholesterol
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