摘要
目的评价MRI T2 mapping成像技术对腰椎间盘退行性变的诊断价值。资料与方法前瞻性纳入2013年10月-2015年12月因腰背部疼痛于复旦大学附属上海市第五人民医院就诊并行腰椎1.5T MRI检查的患者100例。常规矢状位T1WI及T2WI、横断位T2WI,并行正中矢状位T2 mapping成像。根据Pfirrmann标准将475个腰椎间盘分级,测量髓核(NP)及纤维环(AF)前、后缘的T2值。分别比较各级NP和AF前、后缘T2值,并分析T2值、年龄以及分级间的相关性。同时选取30例患者间隔半年行第2次MRI检查,比较前后2次椎间盘T2值的差异。结果腰椎间盘各分级NP的T2值除IV级与V级间差异无统计学意义(P>0.05)外,其余各级间差异均有统计学意义(P<0.05);腰椎间盘NP T2值与各分级呈高度负相关(r=-0.77);30例腰痛患者间隔半年测得椎间盘AF前、后缘及NP T2值间差异均无统计学意义(P>0.05)。结论 T2 mapping成像技术能够定量评估腰椎间盘退行性变程度,尤其是NP的T2值能够较好地反映Ⅰ~Ⅳ级椎间盘退行性变程度的差异,因而可以为诊断腰椎间盘退行性变提供影像学依据。
Purpose To investigate the value of MRI T2 mapping imaging in diagnosis of lumbar intervertebral disc degenerative（IVDD）. Materials and Methods A prospective study was performed on 100 patients who underwent 1.5T MRI examination because of lumbar and back pain from October 2013 to December 2015 at the Fifth People’s Hospital of Shanghai, Fudan University. The MRI examinations included conventional sagittal T1WI and T2WI, axial T2WI and median sagittal T2 mapping imaging. According to Pfirrmann standard, 475 lumbar intervertebral discs were graded. T2 values of nucleus pulposus（NP） and annulus fibrosus（AF） of anteriority and posterior with different grades were measured and compared. The correlations between T2 value, age and grade were further analyzed. 30 patients were selected and underwent a second MR examination after half a year, and the difference of T2 values between the two MR examinations were compared. Results Except for grade IV and grade V, the differences of T2 values of NP between the other grades of lumbar intervertebral discs were statistically significant（P〈0.05）. T2 values of NP were negatively correlated with the grades（r=-0.77）. There were no significant differences in T2 values of NP and AF of anteriority and posterior in 30 patients with back pain between the two MR measurements of half year interval（P〉0.05）. Conclusion T2 mapping imaging can quantitatively assess the degree of IVDD, especially T2 values of NP can reflect the differences of IVDD with grade Ⅰ-Ⅳ, so it can provide the imaging evidence for the diagnosis of IVDD.
作者
温群
孟凡华
钱亭
魏春晓
刘军
肖菁
WEN Qun MENG Fanhua QIAN Ting WEI Chunxiao LIU Jun XIAO Jing(Department of Radiology, the Fifth People＇s Hospital of Shanghai, Fudan University, Shanghai 200240, Chin)
出处
《中国医学影像学杂志》
CSCD
北大核心
2017年第7期531-535,共5页
Chinese Journal of Medical Imaging
基金
上海市闵行区科委课题(2013MHZ068)
关键词
椎间盘移位
腰椎
磁共振成像
Intervertebral disk displacement
Lumbar vertebrae
Magnetic resonance imaging
