摘要
目的评价纤维支气管镜灌洗术在重型颅脑损伤并肺部感染患者中的临床应用价值。方法选取2014年1月-2015年5月来我院就诊的重型颅脑损伤并肺部感染患者72例,分为研究组与对照组,每组36例;对照组患者给予化痰、平喘、抗感染等常规治疗,研究组患者在化痰、平喘、抗感染等治疗的基础上行纤维支气管镜灌洗术,对2组患者的治疗情况、治疗指标、治疗效果及不良反应等进行比较。结果与对照组相比较,研究组患者的病死率(10.01%)显著降低,总有效率(91.67%)显著提高,差异均有统计学意义;研究组患者的肺部啰音消失时间、发热时间、机械通气时间及抗菌药物使用时间均较短,差异均有统计学意义;研究组细菌培养阳性率及血氧饱和度明显升高,患者的感染控制时间及二氧化碳分压明显优于对照组,差异均有统计学意义;2组患者的不良反应相比,差异无统计学意义。结论纤维支气管镜下肺泡灌洗治疗重型颅脑损伤并肺部感染患者临床疗效确切、安全性高,具有重要临床应用价值。
Objective To evaluate the clinical application of bronchoalveolar lavage in patients with severe traumatic brain injury complicated with pulmonary infection. Methods From January 2014 to May 2015 in our hospital,72 severe craniocerebral patients complicated with pulmonary infection were divided into the observation group and the control group,36 cases in each group. The control group was given routine treatment,and the observation group was treated with bronchoalveolar lavage therapy on the basis of conventional treatment. Their treatment indexes,treatment effect and adverse reaction were compared. Results Compared with the control group,the mortality( 10. 01%) decreased significantly,and the total effective rate( 91. 67%) increased significantly in the observation group. Their pulmonary rales disappearing time,heating time,mechanical ventilation time and antibiotics were shorter in the observation group than in the control group. The positive rate of bacteria culture and saturation oxygen increased more obviously in the observation group than in the control group. Their infection control time and PaCO_2 were significantly better in the observation group than in the control group( P < 0. 05). There was no statistically significant difference in adverse reactions between the two groups. Conclusion Bronchoalveolar lavage in treatment of severe craniocerebral injury patients with pulmonary infection is effective and safe,and it has important clinical application value.
出处
《临床肺科杂志》
2017年第9期1602-1604,共3页
Journal of Clinical Pulmonary Medicine
关键词
纤维支气管镜
肺部感染
重型颅脑损伤
临床疗效
fiberoptic bronchoscopy
severe craniocerebral injury
pulmonary infection
clinical efficacy
