摘要
本文报道冠心病患者108例在日常活动情况下,采用Holter 24小时监测,发现60例(55.6%)有心肌缺血发作,总计发作244次,其中无症状性心肌缺血198次(81%)。心肌缺血发作时与发作前的心率比较无明显差异。无症状性心肌缺血发作时ST段下降程度与伴随有胸痛发作时比较,亦无明显差异。在上午6时至12时,无症状性心肌缺血发作频率最高,占55.1%。内服缓释硝酸异山梨酯(消心痛)可以减少心肌缺血发作。
The clinical characteristics of asymptomatic myocardial ischemia have been studied in 108 patients with coronary heart disease. The episodes of myocardial ischemia were according to planar or downslope (80ms) ST-segment depression of 0.1mV lasting for more than 1 minute by ambulatory ECG monitoring (Holter).
This study demonstrated that 60 (55.6%) of 108 patients with coronary heart disease had daily episodes of myocardial ischemia. They had 244 epi sodes of transient myocardial ischemia during daily activity in 24 hours, 198 (81%) of these episodes were asymptomatic. No significant differences were found in heart rate at the time of onset and before ST-segment depression. The magnitude of STsegment depression was not related to the presenceor absence of chest pain. The frequency of episodes of asymptomatic myocardial ischemia peakedin the morning between 6 A. M and 12 A. M, amounted to 55% of the total number of episodes in 24 hours. Slow-release lsosorbide dinitrate could either abolish or decrease the frequency of both silent or painful episodes of myocardial ischemia,
出处
《中国循环杂志》
CSCD
1991年第4期266-268,共3页
Chinese Circulation Journal
关键词
冠心病
心肌缺血
硝酸异山梨酯
Coronary heart disease
Asymptomatic myocardial ischemia