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AMPK与氧化应激及其与运动关系的研究进展 被引量:12

Research Progress of AMPK and Oxidative Stress and Its Relationship with Exercise
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摘要 细胞能量代谢改变可以激活腺苷酸活化蛋白激酶(AMP-activated protein kinase,AMPK),氧化应激同样也能激活AMPK,参与机体抗氧化还原反应的调节。综述AMPK与氧化应激及其与运动关系的最新研究进展,以期为慢性病的形成、防治以及运动性疲劳的发生机制等相关领域的研究提供理论依据。 Changes in cellular energy metabolism can activate AMPK (AMP-activated protein kinase), and oxidative stress can also activate AMPK, which is involved in the regulation of antioxidant response. This paper reviews the latest research progress of the relationship between AMPK and oxidative stress and its relationship with exercise, so as to provide a theoretical basis for the study of the formation and prevention of chronic diseases and the mechanism of exercise-induced fatigue.
作者 罗琳 张缨 LUO Lin ZHANG Ying(Beijing Sport University, Beijing 100084, China Guizhou Normal University, Guiyang 550001, China.)
出处 《中国体育科技》 CSSCI 北大核心 2017年第4期125-130,共6页 China Sport Science and Technology
基金 国家自然科学基金项目(31471134) 中央高校基本科研业务费资助北京体育大学自主课题(2016BS026) 贵州省教育厅青年科技人才成长项目(黔教合KY字[2016]129)
关键词 AMPK 氧化应激 氧化还原反应 能量代谢 运动 AMPK oxidative stress redox reaction energy metabolism exercise
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