摘要
目的:观察生脉注射液在胃癌、肠癌患者Xelox方案化疗中减轻骨髓抑制的效果。方法:选取笔者所在医院2012年5月-2016年11月收治的30例肿瘤患者,随机分为两组。治疗组患者19例,采用生脉注射液60 ml稀释于5%葡萄糖注射液250 ml,静脉滴注,在化疗开始前1天开始用药,1次/d,连用15 d为1个周期;对照组患者11例,仅用化疗。所有病例均接受2个周期化疗,比较两组化疗后,白细胞及血小板变化的例数及程度。结果:治疗后,治疗组白细胞及血小板计数改善情况均明显优于对照组,差异有统计学意义(P<0.05)。结论:生脉注射液在恶性肿瘤化疗时对骨髓抑制有明显的预防和治疗作用,该药对减轻中晚期肿瘤患者的化疗毒性作用有效。
Objective：To observe Shengmai Injection decreasing bone marrow depression of gastric cancer patients and colorectal cancer patients.Method：30 cancer patients in our hospital from May 2012 to November 2016 were selected and randomly divided into two groups.19 patients in the treatment group were treated with 6O ml Shengmai Injection diluted in 250 ml 5% Glucose Injection by intravenous infusion,medication began from the day before the chemotherapy started,once a day,15 days as a cycle;11 patients in the control group were treated with chemotherapy alone,all cases received 2 cycles of chemotherapy.Compared with the change in value and extent of white blood cells and platelet between the two groups after chemotherapy.Result：After the treatment,the change in value and extent of leukocyte and platelet in treatment group were obviously better than those in the control group,the differences were statistically significant（P〈0.05）.Conclusion：Shengmai Injection has obviously preventive and therapeutic effects on bone marrow depression when patients received chemotherapy,the drug has attenuate toxicity effect in chemotherapy of middle-late cancer patients.
出处
《中外医学研究》
2017年第20期25-26,共2页
CHINESE AND FOREIGN MEDICAL RESEARCH
关键词
生脉注射液
恶性肿瘤
化疗
骨髓抑制
减毒
Shengmai Injection
Tumor
Chemotherapy
Bone marrow depression
Attenuate effect
