摘要
目的观察使用聚维酮碘溶液降低气管插管全麻患者气管内细菌的污染程度的可行性。方法 100例在气管插管全麻下行择期手术的患者随机分为试验组(n=50)和对照组(n=50),试验组患者术前0.25%聚维酮碘溶液深漱口,同时插入的气管导管均在0.25%的聚维酮碘溶液浸泡过后干燥无菌;对照组患者术前只用0.9%生理盐水深漱口,插入的无菌气管导管未做任何抗菌处理。在麻醉过程中的不同时间点无菌拭子取样,之后细菌计数培养和鉴定。结果含漱后试验组患者口腔内细菌数明显低于对照组(P<0.05),并且没有检测到耐甲氧西林金黄色葡萄球菌(MRSA)。拔除气管导管后再次口咽部细菌培养也提示聚维酮碘溶液有持续的抑菌杀菌作用(P<0.05),试验组处理方法对于减少口咽部细菌下移、黏附、定植气管内表面更有意义(P<0.05)。结论聚维酮碘溶液用作术前口腔护理和气管导管抗菌处理,可有效预防气管内细菌污染。
Objective Using povidone-iodine liquid to reduce the degree of contamination of tracheal bacteria in patients with tracheal intubation anesthesia. Methods 100 patients who underwent general anesthesia for selective surgery were randomly split into the experimental group（ n = 50） and the control group（ n = 50）. Patients in the experimental group were given 0. 25% povidone-iodine liquid for deep gargle for 2 times and were intubated with a kind of endoracheal tube（ ETT）which was immersed in 0. 25% povidone-iodine liquid before drying and sterile. In the control group,patients gargled with0. 9% physiological saline,but the ETT used in the control group did not receive any measures to prevent infections. Swabs were sampled from the oral cavity and trachea wall using cotton tipped swab for bacterial growth,and then did bacteria cultivate and counting. Results In contrast to control group,the bacterial numbers of experimental groups were dramatically lower after the oral nursing（ P〈0. 05）,and methicillin-resistant Staphylococcus aureus（ MRSA） was not detected out in the experimental group. After extubation the oropharyngeal,bacterial cultivation result also suggested that povidone-iodine has sustained bactericidal effect（ P〈0. 05）. The experimental method was benefit for decreasing the numbers of bacterial colonies of moving down the throats and adhering to as well as colonizing on the inner wall of the trachea significantly. Conclusion Povidone-iodine can effectively prevent the contamination of the bacteria in the trachea,which is utilized for preoperative oral care and antibacterial-processed ETT.
出处
《中国消毒学杂志》
北大核心
2017年第6期528-530,共3页
Chinese Journal of Disinfection
关键词
聚维酮碘
深漱口
细菌寄殖
气管插管
povidone-iodine
deep oral gargle
bacterial colonization
endotracheal intubation
