摘要
目的探讨注意缺陷多动障碍(ADHD)患儿与正常儿童在母孕期外源物暴露情况的差异,分析孕期外源物暴露与ADHD发病的相关性。方法选择2015年1月至2016年10月在安徽省儿童医院就诊102例ADHD患儿为病例组,以同期在儿童保健门诊正常体检的105名非ADHD患儿为对照组,采用自编调查问卷收集两组儿童母亲在其孕期的外源物暴露情况。结果两组儿童的母亲孕期经常接触二手烟、重金属、噪音、孕期患病情况和药物使用的差异有统计学意义(P<0.05),多因素分析显示孕期接触噪音、重金属和患病情况是ADHD发病的危险因素。结论母孕期特定外源物的暴露是ADHD的危险因素,应采取相应措施,避免有害物对母孕期的伤害,降低ADHD发生。
Objective To understand the differences of prenatal exposure to exogenous substances in normal children and children with attention deficit hyperactivity disorders （ADHD）.At the same time, to analyze the correlation between the exogenous exposure during pregnancy and the incidence of the ADHD.Methods Two groups of exogenous substances information in children＇＇s mothers were collected by self-designed questionnaire.There were 102 children with ADHD treated in Anhui Children＇＇s Hospital as the case group from January 2015 to October 2016.In the meantime, there were 105 non ADHD children who had normal physical examination as the control group.Results The differences of case group and control group in the factors of second-hand smoking, heavy metals, noise regular exposure, the prevalence of maternal morbidity and the drug application were statistically significant （P〈0.05）.The regression analysis showed the main risk factors of ADHD were noise, heavy metals and prevalence of maternal morbidity.Conclusion Maternal exposure of specific exogenous substances is a risk factor for the attention deficit hyperactivity disorder, and appropriate measures should be taken to avoid harmful effects on the pregnant women, in order to reduce the incidence of ADHD.
出处
《安徽医学》
2017年第6期718-720,共3页
Anhui Medical Journal
关键词
孕期外源物
注意缺陷多动障碍
病例对照研究
Exogenous substances
Attention deficit hyperactivity disorder
Case-control study
