摘要
目的:探讨表观扩散系数(ADC)值的离散系数对于乳腺良恶性病变鉴别诊断的应用价值。方法:搜集96例患者磁共振乳腺病灶98个,分别测量每一病灶ADC值的均值(x)及标准差(s),并计算每一个病灶ADC值的离散系数CV(CV=s/x)。评估病灶ADC值均值及CV的诊断效能。结果:乳腺良恶性病变组ADC值均值[良性(1.42±0.32)×10^(-3)mm^2/s,恶性(1.04±0.29)×10^(-3)mm^2/s]及CV(良性0.10±0.03,恶性0.17±0.04),两组间均有统计学差异(P<0.0001)。乳腺良性与恶性病变之间ADC-CV差异的效应量(Cohen's d值,1.98)高于良性与恶性病变之间ADC均值差异的效应量(1.25)。ADC-CV ROC曲线的AUC(0.935±0.0227)也显著大于ADC均值ROC曲线的AUC(0.790±0.0447)(P<0.01)。结论:乳腺病变DWI检查中ADC-CV较ADC值均值在诊断乳腺良恶性病变中具有更高的诊断效能。
Objective：To evaluate the usefulness of coefficient variance （CV）of apparent diffusion coefficient （ADC） value in differential diagnosis of benign and malignant breast lesions. Methods：The mean value （x） and standard deviation （s） of ADC value of 98 lesions in 96 patients were measured. The CV of the lesion was denned as CV= s/x. The effieieneies of ADC value and CV were assessed. Results：There was obvious difference between the mean value of ADC [benign （1.42±0.32） ×10^-3mm^2/s,malignant （1.04±0.29）×10^-3mm^2/s] and CV （benign 0.10±0. 03 , malignant 0.17±0.04） of breast lesions （P〈0. 0001）. The Cohen＇s d value of the differentiation of ADC-CV between benign and malignant lesions （1.98） was higher than that of ADC value （1.25）. And the AUC of ROC of CV （0. 935±0. 0227） was significantly greater than that of ADC value （0. 790±0. 0447）（P〈0.01）. Conclusion：Compared with ADC value,ADC-CV can improve the di- agnostic performance of breast lesions.
出处
《放射学实践》
北大核心
2017年第6期569-571,共3页
Radiologic Practice
基金
国家公益性行业科研专项"分子影像学在女性常见恶性肿瘤(乳腺癌
宫颈癌)早期诊断
治疗疗效及预后评估中的应用研究"(201402020)
关键词
乳腺疾病
磁共振成像
诊断
鉴别
Breast diseases
Magnetic resonance imaging
Diagnosis differential
