摘要
目的:观察白头翁合葛根芩连汤内服配合灌肠治疗湿热型溃疡性结肠炎的疗效,并探讨其可能的治疗机理,为治疗溃疡性结肠炎提供新的有效药物。方法:以100例湿热型溃疡性结肠炎患者为研究对象,随机分为治疗组和对照组各50例;治疗组给予白头翁合葛根芩连汤口服并结合灌肠治疗;对照组给予柳氮磺吡啶口服。两个疗程后对比两组治疗后治疗前后中医症状总积分、临床疗效及肠镜下黏膜病变表现。结果:观察组的腹痛、肛门灼热、溲赤症状积分较低于对照组,差异具有统计学意义(P<0.05)。观察组治疗有效率为96.0%,对照组为74.0%,组间比较差异具有显著性(P<0.05)。观察组黏膜病变有效率为98.0%,对照组为76.0%,组间比较差异具有显著性(P<0.05)。结论:中药口服联合灌肠治疗湿热型溃疡性结肠炎疗效优于对照组,且具有治疗成本低、安全性高、患者依从性好等优点。
Objective： To observe the clinical effect of Baitouweng adding Gegenqin Decoction orally medicated combined with enema therapy in patients with damp-heat type of UC （ Ulcerative colitis） , exploring its treatment mechanism and study the effective drug therapy. Methods： 100 patients with damp-heat type of UC were randomly divided into two groups, 50 cases in each group. The observation group adopted the oral traditional Chinese medicine and enema therapy. The controlled group orally took Sulfasalazine. After two treatment courses, the total TCM symptom scores, clinical effect and enteroscopy manifestation of mucosal lesions for two groups was compared. Results ： The TCM symptom scores of stomachache, anal pain and dark urine for the observation group were lower than the controlled group （ P 〈 0. 05） ; the effective rate of the observation group （96. 0% ） was higher than the controlled group （74. 0% ） （P 〈 0. 05 ） ; the display rate of mucosal lesions for the observation group （98. 0% ） was higher than the controlled group （76. 0% ） （ P 〈 0. 05 ）. Conclusion： Orally taking Traditional Chinese medicine and enema therapy has a better effect in patients with damp-heat type of UC. It is featured as lower treatment cost, higher safety and better compliance.
出处
《四川中医》
2017年第6期162-164,共3页
Journal of Sichuan of Traditional Chinese Medicine
关键词
白头翁汤
灌肠
湿热型溃疡性结肠炎
葛根芩连汤
Baitouwen Decoction
Enema
Damp-heat type UC
Gegenqin Decoction Curative effect
