摘要
目的分析索拉非尼运用在晚期肾癌患者治疗中的效果及不良反应观察。方法选择我院2012年9月至2014年9月收治的晚期肾癌患者95例作为本研究对象,均给予患者索拉非尼药物治疗,观察患者治疗效果、不良反应发生情况、总体中位的生存时间、中位无进展的生存总时间。结果经过治疗后,患者治疗总有效率达91.58%,常见的不良反应包括腹泻、疲劳、手足表面皮肤反应等。结论将索拉非尼运用在晚期肾癌患者治疗中,能够有效提升患者整体治疗效果,且安全性较高,值得在临床大力推广使用。
Objective To analyze the use of sorafenib and adverse reactions in the treatment of patients with advanced renal cell carcinoma effect. Methods In our hospital from September 2012 to September 2014 were 95 cases of patients with advanced renal cell carcinoma as the research object, were given drug treatment in patients with sorafenib, to observe the curative effect and adverse reaction of patients, the overall median survival time, median progression free survival time. Results After treatment, the total effective rate was 91.58%, the common adverse reactions include diarrhea, fatigue, hand and foot surface skin reactions, etc. Conclusion The use of Sola Fini in the treatment of patients with advanced renal cell carcinoma, can effectively improve the overall treatment effect of patients, and high safety, it is worth promoting in clinical use.
出处
《中国医药指南》
2017年第15期8-9,共2页
Guide of China Medicine
关键词
索拉非尼
肾癌
不良反应
临床疗效
Sorafenib
Kidney cancer
Adverse effects
Clinical efficacy
