摘要
通过17例严重应激反应及适应障碍病人(应激组)及配对17名健康人(对照组)的心理和免疫测定,发现应激组 SRRS 生活变化单位 (LCU),焦虑抑郁严重程度及人格的神经质倾向均显著高于对照组。外周血淋转反应显著低于对照组,且与应激强度呈负相关;外周血淋巴细胞总数显著高于对照组,并与抑郁呈负相关;24小时尿 MHPG·SO_4 男性病人显著高于对照组男性:且与 STAI 呈正相关。本结果提示应激可引起人体免疫功能明显下降。但涉及问题众多,机理复杂,值得扩大样本,改进方法作进一步研究。
Clinical psychological features and immunological changes in 17 cases di-agnosed with severe stress reaction ahd adjustment disorder as stressed group(SG) were com-pared with that of 17 matched healthy subjects as control group(CG)in this study.It wasfound that SG had a significant higher LUCs in SRRS,severe degress of anxieity and depres-sion and tendency of neurotic personality than that of CG.A lower lymphocyteproliferation,correlated negatively with the stress intensity,and a higher count of periferalblood lymphacyte,negatively coorelated with the scores of depression,were observid in SGwhen compared with that of CG.24 hrs urine MHPG·SO_4in male patients showed a higherrate than that of male controls and positively coorelated with STAL scores.The authorsstressed that significant decreas of human immunological functions after stressful events,though the results has unclosed,it is warrented to have a more larger sample study with im-proved methods in the future since human immunological mechanism involves various fieldsand complex interaction.
出处
《中国心理卫生杂志》
CSSCI
CSCD
北大核心
1991年第2期49-52,共4页
Chinese Mental Health Journal
关键词
应激
免疫抑制
淋转反应
心理卫生
Life change events
stress reaction
adjustment disorder
immunological function
lymphocyte perliferation
can A
MHPG questionnaire
