摘要
目的:观察和评价分析肝动脉灌注化疗栓塞术(TACE)联合复方苦参注射液治疗肝恶性肿瘤的疗效与安全性。方法:选取2013年12月—2015年12月收治的肝恶性肿瘤患者共60例,分析肝动脉灌注化疗栓塞术(TACE)联合复方苦参注射液治疗前后患者肝功能的变化规律。结果:与术前1周比较,术后1 d天冬氨酸氨基转氨酶(AST)、谷氨酸氨基转氨酶(ALT)、直接胆红素(DBIL)及总胆红素(TBIL)均明显升高(P<0.05),术后1周ALT,DBIL及TBIL均明显升高,差异均有统计学意义(P<0.05)。术前1周与术后4~6周患者的Child-Pugh分级A,B级及Child评分差异均有统计学意义(P<0.05)。肝恶性肿瘤患者的肝功能变化与治疗次数、是否合并肝硬化及门脉癌栓相关(P<0.05)。结论:肝动脉灌注化疗栓塞术(TACE)联合复方苦参注射液治疗肝恶性肿瘤患者,效果明显,于30 d左右即可恢复至术前水平,值得临床推广使用。
Objective：To observe the curative effect and security of＇FACE conventional combined with Compound Matfine Injec- tion treatment for the hepatic malignant tumor. Methods ： We selected a total of 60 patients with malignant liver tumorsin December 2013 to December 2015 which were treated with TACE combined with Compound Matrine Injection. Before and after treatment, compare patients＇ liver change rule. Results：Compared with those 1 week before treatment, aspartate amino transaminase （AST）, glutamate amino transaminase （ALT） ,direct bilirubin （DBIL） and total bilirubin （TBIL） 1 d after treatment were significantly increased （ P 〈 0. 05 ）. ALT, TBIL and DBIL1 week after treatment were significantly elevated and the differences were statistically significant （P 〈 0. 05 ）. 1 week before and 4 - 6 weeks after operation, patients＇ Child - Pugh, grade A, grade B and Child score difference had statistical significance （ P 〈 0. 05 ）. Changes in liver function are related to treatment in patients with liver tumor number, whether cirrhosis or door vein tumor emboli （P 〈 0. 05 ）. Conclusion：TACE combined with Compound Matrine Injection treatment of liver in patients with malignant tumor has obvious effect. Recovered to preoperative levels time can be around 30 d. It is worthy of clinical promotion use.
出处
《辽宁中医杂志》
CAS
北大核心
2017年第5期1001-1003,共3页
Liaoning Journal of Traditional Chinese Medicine
关键词
TACE
复方苦参注射液
肝恶性肿瘤
疗效
TACE
Compound Matrine Injection
liver malignant tumor
curative effect
