摘要
目的:比较、分析定量CT(QCT)和MR mDixon-quant对健康人群肝脏脂肪含量测量结果的一致性和相关性。方法:对21位男性和32位女性健康社区居民进行腹部QCT和MR mDixon-quant扫描,QCT分别采用标准计算公式(测量结果记为Fat%QI)和校正后的计算公式(测量结果记为Fat%QR)测量肝脏脂肪含量,并采用MR mDixon-quant测量肝脏脂肪分数(测量结果记为Fat%mD)。比较男、女两组之间的肝脏脂肪含量的测量结果有无差异,比较总体样本QCT与MR mDixon-quant测量结果之间的一致性,并计算相关性系数。结果:QCT及MR mDixon-quant的测量结果均显示,男性与女性的肝脏脂肪含量差异均无统计学意义(P值均>0.05)。总体样本的Fat%QI和Fat%QR分别为(-0.09%±4.88%)和(8.66%±4.41%),Fat%QI显著低于Fat%mD(P<0.01),平均差值为(-6.42%±2.44%),而Fat%QR显著高于Fat%mD(P<0.01),平均差值为(2.33%±2.36%)。Fat%QI、Fat%mD的相关程度(r=0.708,P<0.01)与Fat%QR、Fat%mD的相关程度(r=0.707,P<0.01)近似。结论:与MR mDixon-quant的测量结果相比,使用重新校正的计算公式的QCT能够准确测量中国健康人群的肝脏脂肪含量。
Objective：To compare the consistency and correlation of quantitative computed tomography （QCT） meth- od with MR mDixon-quant method for quantification of hepatic fat content in healthy people. Methods.. Twenty-one men （aged 57-83 years） and thirty-two women （aged 54~80 years） underwent abdomen QCT and MR mDixon-quant examina- tions, and hepatic fat content was determined by two kinds of QCT calculation equations（Fat %QCT（ICRU）, Fat% QCT（revised） ） and MR mDixon-quant fat fraction （Fat%mDixon-quang）. The results were compared between the male and female groups. The re- sults by QCT were compared to MR mDixon-quant, and the correlation coefficients between QCT and MR mDixon-quant were calculated. Results：There was no significant difference in hepatic fat content between men and women in the study group. The mean（ ± standard deviation, SD） of Fat%QCT（ICRU） and Fat %QCT（revised）was （ - 0. 09 % ± 4. 88 %） and （8.66 % ±4.41 %, respectively. Fat%QCT（ICRU） was significantly lower than Fat%mDixion-quant （P〈0.01）, and the mean （ ± SD） of differ- ence was （- 6.42 % ± 2.44 % ）. Fat % QCT（revised） was significantly higher than Fat% mDixon-quant （P〈0.01 ）, and the mean （± SD） of difference was （2.33 %± 2.3 6 % ）. The correlation between Fat %QCT（revised）and Fat%mDixon-quent （r=0. 708, P〈0.01 ） was similar to that between Fat% QCT（ICRU〉 and Fat %mDixox-quant（r= 0. 707, P〈0.01 ）. Conclusion：Compared to MR mDixon-quant, QCT using the revised calculation equations can measure hepatic fat content accurately in healthy Chinese population.
出处
《放射学实践》
北大核心
2017年第5期456-461,共6页
Radiologic Practice
基金
国家自然科学基金青年项目81401407
