摘要
目的综合分析妊娠期糖尿病患者产后代谢指标变化及影响因素研究。方法选取我院2013年7月~2015年10月收治的91例妊娠期糖尿病患者一般资料作为实验组,再选取同期我院前来体检的91例健康妊娠者一般资料作为对照组。两组研究对象均在本院分娩,在研究对象产后12个月后进行随访。分析两组研究对象产后1年糖代谢指标(空腹血糖、口服2 h葡萄糖耐量试验、空腹血脂、体质量以及糖代谢异常)情况、脂代谢(总胆固醇、三酰甘油、低密度脂蛋白胆固醇、高密度脂蛋白胆固醇)、脂代谢异常率以及产后一年代谢综合征(腰围超过80 cm、收缩压超过130 mm Hg、舒张压超过85 mm Hg)发生率等参数指标。结果 (1)两组患者的空腹血糖和口服2 h葡萄糖耐量试验比较无统计学意义(P>0.05);(2)两组患者在三酰甘油、总胆固醇、低密度脂蛋白胆固醇、高密度脂蛋白胆固醇等脂代谢比较无统计学意义(P>0.05);(3)实验组脂代谢异常率显著高于对照组(P<0.05);(4)实验组腰围超过80 cm、收缩压超过130 mm Hg、舒张压超过85 mm Hg异常率显著高于对照组(P<0.05)。结论妊娠期糖尿病患者产后代谢指标变化比较大,其主要影响因素是孕中期空腹血糖。
Objective To comprehensively analyze the changes of postpartum metabolic indices and its influencing fac- tors in the patients with gestational diabetes mellitus.＇ Methods The general data of 91 patients with gestational diabetes mellitus who were admitted to our hospital from July 2013 to October 2015 were selected as the experimental group. The general data of healthy pregnant women who were given physical examination in our hospital during the same period of time were selected as the control group. The two groups of subjects were given delivery in our hospital and they were followed-up 12 months after the delivery. The glucose metabolic indices one year after delivery（fasting blood glucose, 2-hour oral glucose tolerance test, fasting blood lipids, body mass and abnormal glucose metabolism）, lipid metabolism （total cholesterol, triglyceride, low density lipoprotein cholesterol, high density lipoprotein cholesterol）, lipid metabolism abnormalities,incidence rate of postpartum metabolic syndrome one year after the delivery （waist circumference over 80 era, systolic blood pressure over 130 mmHg,diastolic blood pressure over 85 mmHg） and other indices were analyzed in both groups. Results ①There was no statistically significant difference between the two groups in fasting blood glucose and 2-hour oral glucose tolerance test（P〉0.05）; ②there was no statistically significant difference between the two groups in the lipid metabolism of triacylglycerol, total cholesterol,low density lipoprotein cholesterol and high density lipoprotein cholesterol（P〉0.05）;③the abnormal rate of lipid metabolism in the experimental group was significantly higher than that in the control group （P〈0.05）; （~）in the experimental group,the waist circumference was over 80 cm, the systolic blood pressure was more than 130 mmHg, and the diastolic blood pressure wa~ more than 85 mmHg.The abnormal rate in the experimental group was significantly higher than that in the control group（P〈0.05）. Conclusion The postpartum metabolic index in the patients with gestational diabetes mellitus is relatively large, and the main influencing factor is the fasting blood glucose in the second trimester.
出处
《中国现代医生》
2017年第13期61-64,共4页
China Modern Doctor
基金
浙江省医学会临床科研基金项目(2012ZYC-A86)
关键词
妊娠期糖尿病患者
产后
代谢指标变化
影响因素研究
Gestational diabetes mellitus
Postpartum
Changes of metabolic indices
Influence factor research
