摘要
目的探讨中晚期宫颈鳞癌患者放化疗后复发未控的危险因素,为提高患者生存率提供依据。方法收集132例中晚期宫颈鳞癌患者的临床资料,对放化疗后复发未控的危险因素进行Logistic回归分析。结果 132例患者中,31例(23.48%)出现了复发未控。研究发现,有淋巴结转移、肿瘤直径≥4 cm、分化程度低、放疗时间﹥8周、化疗疗程﹤3个疗程、放疗剂量﹥85 Gy、治疗前血红蛋白水平﹤60 g/L是肿瘤复发的危险因素。结论对于中晚期宫颈鳞癌患者,需根据患者体征选择合适的治疗方案,对于低分化、肿瘤直径大、出现淋巴结转移以及治疗前血红蛋白含量低的患者需加强注意。
Objective To investigate the risk factors of uncontrolled recurrence in patients with advanced cervical squamous cell carcinoma （SCC）, and to provide scientific reference for improving survival of patients. Method A total of 132 patients with advanced cervical SCC were included in the analysis. Logistic regression analysis was utilized to evaluate risk factors of controlled recurrence after treatment. Result Of the 132 cases, 31 （23.48%） cases had uncon- trolled recurrence. The analysis showed that, lymph node metastasis, tumor diameter≥ 4 cm, poor differentiation, radio- therapy 〉 8 weeks, chemotherapy cycle 〈 3, radiation dose 〉85 Gy, hemoglobin 〈 60 g/L before treatment were risk fac- tors of tumor recurrence. Conclusion For the patients with advanced cervical SCC, individualized therapy should be es- tablished, and more attention should be paid to those with poor differentiation, large tumors, lymph node metastasis and low level of hemoglobin before treatment.
出处
《癌症进展》
2017年第3期331-333,共3页
Oncology Progress
关键词
中晚期宫颈鳞癌
放化疗
复发未控
advanced cervical squamous cell carcinoma
radiotherapy and chemotherapy
uncontrolled recurrences
