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阿司匹林联合氢氯吡格雷治疗反复TIA的疗效观察

Observation on the Curative Effect of Aspirin Combined with Clopidogrel Hydrogen in the Treatment of Recurrent TIA
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摘要 目的观察阿司匹林联合氢氯吡格雷治疗反复短暂性脑缺血发作(TIA)的效果。方法选取我院收治的38例TIA患者,随机分为治疗组和对照组各19例。对照组采用阿司匹林抗血小板治疗,治疗组在此基础上联合氢氯吡格雷治疗。比较两组患者的疗效、治疗前后的凝血功能指标和发病次数。结果治疗前,两组患者的凝血功能指标、发病次数比较差异无统计学意义(P>0.05)。治疗后,与对照组比较,治疗组的凝血功能改善,发病次数减少,差异均有统计学意义(P<0.05)。治疗组的总有效率为94.74%,显著高于对照组的68.42%,差异有统计学意义(P<0.05)。结论阿司匹林联合氢氯吡格雷治疗反复TIA患者,可有效改善患者的临床症状,恢复机体凝血功能,减少发病次数。 Objective To observe the effect of aspirin combined with clopidogrel hydrogen in the treatment of recurrent transient ischemic attack (TIA). Methods 38 cases of patients with TIA admitted to our hospital were selected and randomly divided into treatment group and control group, with 19 cases in each group. The control group received aspirin antiplatelet therapy, while the treatment group was treated with clopidogrel hydrogen on this basis. The curative effect, indicators of blood coagulation and attack times before and after treatment were compared between two groups. Results Before treatment, no statistical difference was found in the indicators of blood coagulation and attack times between two groups (P〉0.05). Compared with those of control group after treatment, the blood coagulation of treatment group improved and the attack times decreased, with statistical differences (P 〈0.05). The total effective rate of treatment group was 94.74%, significantly higher than 68.42% of control group, with statistical difference (P 〈0.05). Conclusions Aspirin combined with clopidogrel hydrogen in the treatment of recurrent TIA can effectively improve patients' symptoms, recover the body's blood coagulation and reduce the attack times.
出处 《临床医学工程》 2017年第5期641-642,共2页 Clinical Medicine & Engineering
关键词 疗效 发病次数 阿司匹林 氢氯吡格雷 TIA Curative effect Attack times Aspirin Clopidogrel hydrogen TIA
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