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2013-2015年血流感染病原菌的分布及耐药性变迁 被引量:4

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摘要 目的了解医院2013年1月至2015年12月血培养病原菌分布和耐药性变化。方法采用美国赛默飞公司Versa TREK 96全自动血培养仪进行培养,阳性标本用西门子MicroScan WalkAway40Plus全自动微生物鉴定仪进行菌种鉴定和药敏试验,应用WHONET 5.6软件对结果进行统计分析。结果 5 624份血培养标本分离出病原菌345株,阳性率为6.13%;革兰阴性菌174株,占50.4%;革兰阳性菌163株,占47.3%;真菌8株,占2.3%。检出率前5位的是表皮葡萄球菌(16.3%,56/345)、大肠埃希菌(15.9%,55/345)、金黄色葡萄球菌(9.9%,34/345)、肺炎克雷伯菌(8.5%,29/345)和鲍曼不动杆菌(6.10%,21/345)。碳青霉烯类抗菌药对大肠埃希菌和肺炎克雷伯菌抗菌活性最强,对鲍曼不动杆菌抗菌活性较差;革兰阳性球菌对糖肽类和利奈唑胺抗菌药物高度敏感。结论血培养分离的病原菌菌种复杂、耐药性呈增长趋势,临床应积极开展病原菌分布及其耐药性监测及时调整抗菌药物用药。
出处 《国际检验医学杂志》 CAS 2017年第10期1412-1415,共4页 International Journal of Laboratory Medicine
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