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非酒精性脂肪性肝病与动脉粥样硬化 被引量:5

Atherosclerosis in patients with nonalcoholic fatty liver disease
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摘要 随着生活饮食规律的改变,基于胰岛素抵抗的非酒精性脂肪性肝病(Nonalcoholic fatty liver disease,NAFLD)患病率不断上升,但仅有不超过1%的NAFLD患者发生肝硬化,而发生心脑血管疾病的风险远远高于肝硬化.Ekstedt et al进行的一项持续13.7年的随访研究显示,在经肝活检病理学检查证实为NAFLD患者中,仅有10%发生终末期肝病,发生心脑血管疾病的比例高达29%.近年来,多项研究证实动脉粥样硬化性心血管疾病是NAFLD患者最重要的转归.
作者 何方平
出处 《实用肝脏病杂志》 CAS 2017年第3期263-266,共4页 Journal of Practical Hepatology
基金 国家自然科学基金资助项目(编号:81360138)
关键词 非酒精性脂肪性肝病 动脉粥样硬化 内皮功能 炎症 Nonalcoholic fatty liver disease Atherosclerosis Endothelial function Inflammation
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