摘要
实验以20%KOH/活性炭(AC)为催化剂,采用绿色环保的碳酸二甲酯为甲基化试剂,在高压釜中,高选择性合成了1-甲基咪唑。考察了温度、时间、投料比、压力对反应的影响,当温度150℃,n(碳酸二甲酯)/n(咪唑)=1.1,釜内最大压力3 MPa,反应2h,1-甲基咪唑产率最高,97%。该工艺不使用溶剂,绿色无污染,具有工业化应用前景。
A highly selective synthetic method of 1 - methylimidazole was reported, using 20% KOH/AC as catalyst,environmentally friendly dimethyl carbonate as methylating agent. The effects of reaction temperature, time, feed ratio andpressure on the yield of 1 - methylimidazole were also investigated. The results showed that when the reaction temperature is150℃, n（dimethyl carbonate）/n（imidazole） = 1.1, maximum pressure 3 MPa and the reaction time is 3 hours, the yield of 1-methylimidazole reached 97%. This process avoiding use organic solvent, is a green way with good industrial prospect.
作者
薛其才
郑化安
张生军
寇永利
王文涛
聂颖颖
Xue Qicai Zheng Huaan Zhang Shengjun Kou Yongli Wang Wentao Nie Yingymg(Shaanxi Coal and Chemical Technology Institute Co. , Ltd. , Xi~n 710065, China State Energy Key Laboratory of Clean Coal Grading Conversion, Xi~n 710065, China)
出处
《山东化工》
CAS
2017年第8期44-46,共3页
Shandong Chemical Industry
关键词
1-甲基咪唑
碳酸二甲酯
无溶剂
绿色合成
1 - methylimidazole
diethyl carbonate
solvent - free
green synthesis
