摘要
目的对比经尿道等离子体电切术(PKRBT)与2μm钬激光切除术(HOLBT)治疗浅表性膀胱癌的效果与安全性。方法择取2012年1月至2015年1月我院收治的62例浅表性膀胱癌患者为研究对象,依据入院先后顺序随机分为两组,各31例,A组行PKRBT治疗,B组行2μm HOLBT治疗,观察并比较两组治疗疗效。结果与A组相比,B组的术中出血量明显减少,手术时间明显缩短,差异有统计学意义(P<0.05),但术后导尿管留置时间及住院时间无统计学意义(P>0.05);治疗后,两组的血清IL-6、IL-10及TNF-α水平均上升,但与A组相比,B组的IL-6、TNF-α水平明显降低,IL-10水平明显上升,差异有统计学意义(P<0.05);治疗及随访期间,与A组相比,B组的并发症发生率及复发率显著降低,差异有统计学意义(P<0.05)。结论对于浅表性膀胱癌患者,采用2μm HOLBT治疗效果良好,且并发症较少,并减少机体的炎症水平,故临床应用价值较高。
Objective To compare the efficacy and safety of transurethral plasmakinetic resection of the prostate （PKRP） and 2 μm holmium laser resection of the prostate （HOLRP） in the treatment of superficial bladder cancer.Methods From January 2012 to January 2015,62 cases of superficial bladder cancer patients in our hospital were chosen as the research subjects.According to the admission order,they were randomly divided into two groups,each with 31 cases.Group A underwent PKRP treatment,while group B received 2 μm HOLRP treatment.The therapeutic effect of the two groups were observed and compared.Results Compared with group A,group B experienced significantly less blood loss,shorter operative time,and the difference was statistically significant （P〈0.05）,but with no significant difference （P〉0.05） in postoperative catheter indwelling time and hospitalization time.After treatment,the serum levels of IL-6,IL-10 and TNF-α increased in both groups,but compared with group A,the levels of IL-6 and TNF-α in group B were significantly lower,while IL-10 was significantly higher,with statistically significant difference（P〈0.05）.During treatment and follow-up period,compared with group A,the incidence of complications and recurrence rate in group B was significantly reduced,with statistically significant difference（P〈0.05）.Conclusion For patients with superficial bladder cancer,2 μm HOLRP proves to be effective,with fewer complications,and reduced level of body inflammation,so it is of high clinical application value.
出处
《锦州医科大学学报》
CAS
2017年第2期37-39,共3页
Journal of Jinzhou Medical University
关键词
浅表性膀胱癌
经尿道电切术
2μm激光切除术
并发症
superficial bladder cancer
transurethral resection
2 μm holmium laser resection
complication
