摘要
[目的]观察小青龙汤联合西药治疗慢性支气管炎急性发作疗效。[方法]使用随机平行对照方法,将82例住院患者按病志号抽签方法简单随机分为两组。对照组41例抗感染、止咳和平喘、吸氧、化痰等;头孢哌酮1~2g+葡萄糖100~200mL,1次/12h。治疗组41例小青龙汤,半夏~制15g,麻黄~炙、白芍各10g,五味子9g,桂枝、甘草~炙各6g,干姜、细辛各3g,外感缓解,咳嗽,去桂枝,加葶苈子20g,杏仁10g;发热严重,去桂枝、干姜,加鱼腥草15g、黄芩10g;体质较弱,加黄芪30g,党参15g,白术10g,水煎200mL,1剂/d,2次/d;西药治疗同对照组。连续治疗2周为1疗程。观测临床症状、WBC分类计数、肺部影像、咳嗽消失、喘息消失、咳痰消失、住院时间、不良反应。治疗1疗程(2周),判定疗效。[结果]治疗组痊愈20例,显效12例,有效7例,无效2例,总有效率95.12%;对照组痊愈13例,显效9例,有效8例,无效11例,总有效率73.17%;治疗组疗效优于对照组(P<0.01)。咳嗽消失、喘息消失、咳痰消失、住院时间治疗组优于对照组(P<0.05,P<0.01)。[结论]小青龙汤加味联合西药治疗慢性支气管炎急性发作,疗效满意,无严重不良反应,值得推广。
[Objective] To observe the therapeutic effect of Xiaoqinglong decoction combined with western medicine on acute exacerbation of chronic bronchitis. [Methods] Randomized parallel control method was used to divide 82 inpatients into two groups according to the method of lot number. The control group 41 cases of anti-infection, cough and asthma, oxygen, phlegm, etc.; cefoperazone 1-2g＋glucose 100-200mL, 1/12h. Treatment group of 41 cases of small Qinglong soup, Pinellia 15g, ephedra Sunburn, white peony root 10g, Schisandra 9g, cassia twig, Zhigancao 6g, ginger, Asarum 3g, exogenous relief, cough, Astragalus 30g, Codonopsis 15g, Atractylodes 10g, decoction 200mL, 1 dose/d, to the Guizhi, ginger, add Houttuynia 15g, Scutellaria 10g; 2 times/d; Western medicine treatment with the control group. Continuous treatment for 2 weeks for a course of treatment. The clinical symptoms, WBC count, lung image, cough disappeared, wheezing disappeared, sputum disappeared, hospitalization time, adverse reactions. Treatment of a course of treatment （2 weeks）, determine the efficacy. [Results] In the treatment group, 20 cases were cured, 12 markedly effective, 7 effective and 2 ineffective. The total effective rate was 95.12%. In the control group, 13 cases were cured, 9 markedly effective, 8 effective and 11 ineffective. The total effective rate was 73.17%; The curative effect of the treatment group was better than that of the control group （P〈0.01）. Cough disappeared, wheezing disappeared, sputum disappeared, the hospital stay in the treatment group than the control group （P 〈0.05, P〈0.01）. [Conclusion] Xiaoqinglong decoction combined with western medicine treatment of acute exacerbation of chronic bronchitis, satisfactory results, no serious adverse reactions, should be promoted.
出处
《实用中医内科杂志》
2017年第4期53-55,共3页
Journal of Practical Traditional Chinese Internal Medicine
