摘要
[目的]观察柴胡加龙骨牡蛎汤治疗中风后失眠疗效。[方法]使用随机平行对照方法,将60例住院患者按病志号抽签方法简单随机分为两组。对照组30例艾司唑仑,1mg/次,睡前服用。治疗组30例柴胡龙骨牡蛎汤:柴胡、煅龙骨、煅牡蛎、煅磁石、黄芩、半夏、桂枝、党参等,水煎300mL,1剂/d,早晚温服。连续治疗4周为1疗程。观测临床症状、汉密尔顿焦虑量表(HAMA)、抑郁评量表(HAMD)、匹兹堡睡眠指数(PSQI)、不良反应。治疗1疗程(4周),判定疗效。[结果]治疗组显效20例,有效9例,无效1例,总有效率96.67%;对照组显效10例,有效8例,无效12例,总有效率60.00%;治疗组疗效优于对照组(P<0.01)。焦虑量表评分两组均有改善(P<0.05,P<0.01),治疗组改善优于对照组(P<0.01)。抑郁量表评分两组均有改善(P<0.05,P<0.01),治疗组改善优于对照组(P<0.01)。匹兹堡睡眠指数两组均有改善(P<0.01),治疗组改善优于对照组(P<0.01)。[结论]柴胡加龙骨牡蛎汤治疗中风后失眠,疗效满意,无严重不良反应,值得推广。
[Objective] To observe the therapeutic effect of Bupleurum chinense plus Decoction on treating insomnia after stroke. [Method] 60 patients were randomly divided into two groups according to the random number method. 30 cases of the control group estazolam, 1 mg/time, bedtime. The treatment group of 30 cases Oyster Soup entrapement keel： bupleurum, calcined keel, calcined oyster, calcined magnet, scutellaria root, pinellia tuber, cassia twig, Radix Codonopsis, Decoction 300mL, 1 doses of/d, sooner or later. Continuous treatment for 4 weeks for 1 courses. Clinical symptoms, Hamilton Anxiety Scale （/-lAMA）, Depression Rating Scale （HAMD）, Pittsburgh sleep index （PSQI）, adverse reactions were observed. Treatment for 1 courses （4 weeks）, determine the efficacy. [Result] In the treatment group, 20 cases were markedly effective, effective in 9 cases, ineffective in all cases, the total effective rate was 96.67%, the control group was markedly effective in 10 cases, effective in 8 cases, ineffective in 12 cases, the total effective rate was 60%; the treatment group was better than the control group （P〈0.01）. Anxiety scale scores of the two groups were improved （P〈0.05, P〈0.01）, the treatment group was better than the control group （P〈0.01）. Depression Scale score of two groups were improved （P〈0.05, P〈0.01）, the treatment group was better than the control group （P〈0.01）. The sleep index of the two groups of Pittsburgh improved （P〈0.01）, the treatment group was better than the control group （P〈0.01）. [Conclusion] The curative effect of Bupleurum chinense and the oyster shell Decoction in treating insomnia after apoplexy was satisfactory, and no serious adverse reactions were found.
出处
《实用中医内科杂志》
2017年第4期17-20,共4页
Journal of Practical Traditional Chinese Internal Medicine
