摘要
目的 探讨瞬时弹性波扫描仪在慢性乙型肝炎患者肝纤维化诊断中的应用价值.方法 选取慢性乙型肝炎患者124例,采用瞬时弹性波扫描仪对患者进行肝脏硬度（LSM）测量,取连续10次测量结果的平均值,并对患者的血清纤维化指标进行检查和上腹部核磁共振成像并检查.对比两种检查诊断的符合率.结果 重度肝纤维化患者LSM值（24.65 ±8.54）,显著高于轻度肝纤维化患者的（5.46 ±2.11）和中度肝纤维化患者的（8.96±6.75）（t=12.871、8.254,均P〈0.05）.LSM值与血清学肝纤谱之间诊断符合率为87.8％,行上腹部MRI检查的患者中,检查结果提示二者诊断肝硬化的符合率为79.2％,差异有统计学意义（χ^2=2.866,P〈0.05）.结论 瞬时弹性波扫描仪在慢性乙型肝炎患者肝纤维化诊断中具有较高的诊断价值,对患者无创伤,诊断符合率高,易被患者接受,值得广泛推广应用.
Objective To explore the application value of transient elastic wave scanner in the diagnosis of chronic hepatitis B （CHB） patients with liver fibrosis.Methods 124 patients with CHB were randomly selected.The instantaneous elastic wave scanner （LSM） was taken in patients with liver stiffness measurement,an average of 10 consecutive measurements of the value,and the abdominal MRI examination and the indicators of serum fibrosis of the patients were checked.The coincidence rate of the diagnosis of the two kinds of examination was compared.Results The LSM value of patients with severe liver fibrosis was （24.65 ± 8.54）,which was significantly higher than （5.46 ± 2.11） of patients with mild liver fibrosis and （8.96 ± 6.75） of patients with moderate hepatic fibrosis,the differences were statistically significant（t =12.871,8.254,all P 〈 0.05）.The LSM value between serum liver fibrosis and spectrum diagnosis rate was 87.8%,with abdominal MRI examination of patients,results suggested that the two cirrhosis diagnosis coincidence rate was 79.2%,the difference was statistically significant （χ^2 =2.866,P 〈 0.05）.Conclusion The clinical value of the instantaneous elastic wave scanner is high in the diagnosis of hepatic fibrosis in patients with CHB,with no trauma to the patients,the diagnosis coincidence rate is high,easy to be accepted,it is worthy of widely used.
出处
《中国基层医药》
CAS
2017年第8期1254-1256,共3页
Chinese Journal of Primary Medicine and Pharmacy
关键词
慢性乙型肝炎
肝纤维化
瞬时弹性波扫描仪
应用
Chronic hepatitis B
Liver fibrosis
Transient elastic wave scanner
Application
