摘要
从雷公藤(Tripterygium wilfordii Hook.f.)的根中分离得到7个化合物,经1H NMR、13C NMR和MS鉴定为β-谷甾醇(1)、丁香醛(2)、雷公藤乙素(3)、3-羟基-1-(4-羟基-3-甲氧基苯基)丙酮(4)、5,5'-二甲氧基落叶松脂素(5)、新刺五加酚(6)和16-羟基山海棠酸-18-O-β-D-葡萄糖苷(7)。其中化合物2、4、5和6为首次从雷公藤属植物中分离得到。采用热重和差热分析技术研究了雷公藤乙素(3)、新刺五加酚(6)以及雷公藤活性成分雷公藤内酯甲和去甲泽拉木醛的热稳定性。结果表明:雷公藤乙素、新刺五加酚、雷公藤内酯甲和去甲泽拉木醛的热分解温度均大于200℃。结果可为雷公藤质量标准以及雷公藤煨制机理研究奠定基础。
Seven compounds were isolated from the radix of Tripterygium wilfordii Hook. f.. Their structures were identified as β-sitosterol （ 1 ）, syringaldehyde （ 2 ）, tripdiolide （ 3 ）, β-hydroxypropiovanillone （ 4 ）, 5, 5＇-dimethoxylariciresinol （ 5 ）, neociwujiaphenol （6） and wilfordoside A（7）. Compounds 2,4,5 and 6 were isolated from genus of T. wilfordii for the first time. Thermal decomposing curves of compounds 3,6, wilforlide A and demethylzeylasteral were obtained in the nitrogen atmosphere by TG-DTG and DTA techniques. The results indicated that the four tested compounds should be stable under 200℃. This study could lay a foundation for the quality standard and roasting mechanism of T. wilfordii.
出处
《林产化学与工业》
EI
CAS
CSCD
北大核心
2017年第2期72-78,共7页
Chemistry and Industry of Forest Products
基金
江西省教育厅科技重点项目(GJJ150832)
江西省自然科学基金项目(20151BAB205075)
关键词
雷公藤
化学成分
热稳定性
Tripterygium wilfordii
chemical constituent
thermal stability
