摘要
目的探讨偏头痛患者的跨时决策是否受损。方法采用跨时决策（Intertemporalchoice）范式，对30名偏头痛患者及30名健康对照进行跨时决策的研究。结果（1）偏头痛组选择延迟的较大奖赏选项的比例显著低于健康对照组，分别为（18．15±17．53）％和（35．37±20．70）％，差异有统计学意义（t=3．31，P〈0．05）。在now选择条件下和not—now选择条件下偏头痛组[（18．33±21．00）％，（17．96±18．09）％]选择延迟的较大奖赏（long large reward，LL）选项的比例均低于健康对照组[（35．56±21．52）％，（35．19±22．05）％]，差异有统计学意义（t=3．31，P〈0．05；声3．14，P〈0．05）。（2）Pearson相关分析显示色字干扰试验结果与now条件下LL选择比例（r=0．49，P=0．006）及总的LL选择比例（r=0．42，P=0．021）显著正相关。结论偏头痛患者跨时决策能力明显受损，跨时决策与执行功能相关。
Objective To investigate whether there are changes in the ability of intertemporal choices in migraine sufferers. Method Thirty migraine sufferers and thirty healthy controls were investigated by Delay-discount Test. Results （ 1 ） The ratio of later-large （LL） choice in migraine suffers （ （ 18.15 ± 17.53） % ） was significantly lower than that in the healthy controls （（ 35.37± 20.70）% ） , and the difference was statistically significant（t= 3.31, P〈0.05 ）.Under the immediate option for now selection conditions and no immediate option for not-now selection conditions, the ratio of later-large （LL） choice in migraine suffers （（18.33±21.00）% , （17.96± 18.09）%） was also significantly lower than that in the healthy controls （ （35.56±21.52） %, （ 35.19±22.05 ） % ）, and the difference was statistically significant（t= 3.31, P〈0.05 ; t= 3.14, P〈0.05）. （2） Pearson correlation analysis showed that the Stroop Test of migraineurs was positively correlated with LL selection ratio under now conditions （r= 0.49, P= 0.006） and total LL selection （r= 0.42, P= 0.021 ） . Conclusion The ability of intertemporal choices in migraine sufferers has been impaired, which is correlated with executive function.
作者
吴兴启
代迎菊
马慧娟
柏同健
高建国
汪凯
Wu Xingqi Dai Yingju Ma Huijuan Bai Tongjian Gao Jianguo Wang Kai(Department of Neurology, the First Affiliated Hospital of Anhui Medical University, Hefei 230022, Chin)
出处
《中华行为医学与脑科学杂志》
CAS
CSCD
北大核心
2017年第3期226-231,共6页
Chinese Journal of Behavioral Medicine and Brain Science
基金
国家自然科学基金项目（81300944,91232717）
关键词
偏头痛
跨时决策
自我控制
决策
Migraine
Intertemporal-choice
Self-control
Decision-making
