增加倍他乐克剂量对老年慢性心力衰竭患者心功能的影响被引量：5

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摘要目的探讨不同剂量倍他乐克对老年慢性心力衰竭患者心功能的影响。方法选取46例长期服用小剂量倍他乐克的老年慢性心力衰竭患者,在不改变日常用药的基础上逐步增加倍他乐克的剂量,直至达到或接近目标剂量,采用自身前后对照的方法,观察调药前后心功能及临床指标的变化。结果调药后20例患者的心功能较服用小剂量倍他乐克时有所改善(46.5%,P<0.05),平均左室射血分数(LVEF)较前增加了7.6%(P<0.05),平均N-末端脑钠尿肽原(NT-Pro-BNP)降低了28.1%(P<0.01),平均最大可耐受剂量为122.55 mg,剂量与不良反应发生率之间无显著相关性(r=0.42,P>0.05)。结论调整倍他乐克至目标剂量或最大可耐受剂量可明显改善老年慢性心力衰竭患者的心功能。

作者徐晓晖刘斌

机构地区海军上海水电路离职干部休养所海军上海东体育会路离职干部休养所

出处《东南国防医药》 2017年第1期81-82,共2页 Military Medical Journal of Southeast China

关键词老年慢性心力衰竭倍他乐克

分类号 R541.6 [医药卫生—心血管疾病]

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