摘要
目的比较冠状动脉非梗阻性狭窄患者与冠心病患者的血压变异性特点。方法选择经冠状动脉造影示冠状动脉血管狭窄均〈50％的52例患者为冠状动脉非梗阻性狭窄组，至少一支冠状动脉血管狭窄≥50％的53例患者为冠心病组，并在相同条件下行动态血压监测，同时收集两组患者的临床指标，包括性别、年龄、高血压病史、血脂、糖化血红蛋白、同型半胱氨酸、吸烟史，比较两组患者的血压变异性及各临床指标。结果冠状动脉非梗阻性狭窄组患者的全天收缩压变异性、全天舒张压变异性、白天收缩压变异性、白天舒张压变异性、夜间收缩压变异性及夜间舒张压变异性均低于冠心病组，其中全天收缩压变异性及夜间舒张压变异性两组比较差异有统计学意义（P〈0．05）。结论血压变异性是冠状动脉狭窄程度的一项重要预测指标，与冠状动脉病变的严重程度相关。
Objective To investigate the characteritics of blood pressure variability between patients with non obstructive coronary artery stenosis and patients with coronary heart disease. Methods The patients underwent coronary angiography（CAG） were divided into non obstructive coronary artery stenosis group（ all coronary stenosis 〈 50% , n = 52 ） and coronary heart disease group（ at least one coronary stenosis ≥50% , n = 53 ）. Under the same condition, the 24-hour ambulatory blood pressure monitoring was made for the two groups. The clinical indicators including gender, age, hypertension history, blood lipids, glycosylated hemoglobin, homocystenie, smoking were colected, and the blood pressure variability and clinical indicators between the two groups were compared. Results All day systolic blood pressure variability, all day diastolic blood pressure variability, daytime systolic blood pressure variability, daytime diastolic blood pressure variability, nighttime systolic blood pressure variability, nighttime diastolic blood pressure variability all decreased in non obstructive coronary artery stenosis group compared with coronary heart disease group, all day systolic blood pressure variability and nighttime diastolic blood pressure variability showed significant differences between the two groups （P 〈 0. 05 ）. Conclusions Blood pressure variability is an important predictor of coronary artery disease, and is correlated with the severity and incidence of coronary atherosclerosis.
出处
《中国实用医刊》
2017年第5期1-3,共3页
Chinese Journal of Practical Medicine
关键词
冠状动脉非梗阻胜狭窄
冠心病
血压变异性
Non obstructive coronary artery stenosis
Coronary heart disease
Blood pressure variability
