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复方苦参注射液联合化疗治疗非小细胞肺癌临床研究 被引量:13

Clinical Study of Compound Matrine Injection Combined with Chemotherapy in the Treatment of Non-Small Cell Lung Cancer
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摘要 目的:观察复方苦参注射液联合化疗治疗非小细胞肺癌的临床疗效。方法:将收治的全部76例非小细胞肺癌患者按照随机数字表法分为治疗组和对照组各38例。对照组采用紫杉醇合顺铂化疗治疗,治疗组在对照组治疗的基础上加用复方苦参注射液治疗,治疗21 d为1个疗程。2个疗程后观察两组的近期疗效、生活质量改善情况和不良反应情况,并进行比较。结果:近期疗效两组比较无显著性差异(P>0.05),治疗组的生活质量改善情况和不良反应情况明显好于对照组(P<0.05)。结论:复方苦参注射液联合化疗治疗非小细胞肺癌可明显提高疗效、改善生活质量、降低不良反应。 Objective: To observe the clinical efficacy of compound matrine injection combined with chemotherapy in the treatment of non-small cell lung cancer. Methods: All 76 patients with non-small cell lung cancer were randomly divided into the treatment group and the control group,each with a total of 38 cases. The control group was treated with paclitaxel combined with cisplatin chemotherapy,while the treatment group was treated with compound matrine injection on the basis of the control group.The treatment course was 21 days. After 2 courses of treatment,the short-term efficacy,quality of life and adverse reactions of the two groups were observed and compared. Results: There was no significant difference between the two groups( P〈0. 05),and the quality of life and adverse reaction of the treatment group were significantly better than those of the control group( P〈0. 05).Conclusion: Compound matrine injection combined with chemotherapy in the treatment of non-small cell lung cancer can significantly improve the curative effect,improve the quality of life and reduce adverse reactions.
机构地区 阳春市人民医院
出处 《辽宁中医杂志》 CAS 北大核心 2017年第3期556-557,共2页 Liaoning Journal of Traditional Chinese Medicine
关键词 非小细胞肺癌 复方苦参注射液 化疗 non-small cell lung cancer compound matrine injectin chemotherapy
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