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ONGene:A literature-based database for human oncogenes 被引量：3

ONGene:A literature-based database for human oncogenes
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摘要 During oncogenesis,the hyper-activation of proto-oncogenes and defection of tumor suppressor genes（Zhao et al.,2012,2016a）can regulate cell proliferation,differentiation,apoptosis,and cell-to-cell communication（Balmain et al.,2003;Haber and Settleman,2007）.Recent evidence has shown that non-coding RNAs, such as microRNAs （miRNAs） （Chen, 2005）, and long non- coding RNAs （lncRNAs）, can also act as oncogenes to initiate and promote cancer progression. During oncogenesis,the hyper-activation of proto-oncogenes and defection of tumor suppressor genes（Zhao et al.,2012,2016a）can regulate cell proliferation,differentiation,apoptosis,and cell-to-cell communication（Balmain et al.,2003;Haber and Settleman,2007）.Recent evidence has shown that non-coding RNAs, such as microRNAs （miRNAs） （Chen, 2005）, and long non- coding RNAs （lncRNAs）, can also act as oncogenes to initiate and promote cancer progression.
作者 Yining Liu Jingchun Sun Min Zhao
机构地区 School of Engineering School of Biomedical Informatics
出处 《Journal of Genetics and Genomics》 SCIE CAS CSCD 2017年第2期119-121,共3页 遗传学报（英文版）
关键词 Haber proto suppressor oncogene abstracts carefully keyword screening regulate endometrial Haber proto suppressor oncogene abstracts carefully keyword screening regulate endometrial
分类号 R730.2 [医药卫生—肿瘤]
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Journal of Genetics and Genomics
2017年 第2期

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