摘要
二苯基乙二酮及邻苯二胺为原料,蒙脱土负载氯化锌催化合成喹喔啉类化合物,考察溶剂、反应时间、温度、原料物质的量比等对产率的影响.筛选出最佳反应条件为:二苯基乙二酮与邻苯二胺物质的量比为1.2∶1.0,催化剂用量为二苯基乙二酮的10%(x),乙酸乙酯作溶剂,反应时间为10 min,温度30℃.产率最高为96.3%.所得化合物通过熔点、红外、核磁确认.
Quinoxaline derivatives were synthesized by using benzil and o-phenylene diamineas as raw materials and montmorillonitesupportedzinc chloride as catalyst. The effect of solvent, reaction time, temperature and molar ratio of raw materials on the yield were investigated.The optimal reaction conditions were obtained as benzil and o-phenylenediamine molar ratio of 1.2 ： 1.0, the amount of catalyst 10 mol% benzil, and ethyl acetate as the solvent,the reaction time 10 min, temperature 30 ℃ with yield up to 96.3%.The resulting compound were confirmed by melting point, IR and 1 H NMR.
出处
《云南大学学报（自然科学版）》
CAS
CSCD
北大核心
2017年第2期288-293,共6页
Journal of Yunnan University(Natural Sciences Edition)
基金
国家自然科学基金(21362006)
贵州省科技厅科技合作项目(黔科合LH字[2016]7218号)
贵州省科技厅科技支撑计划(黔科合支撑[2016]2311)
关键词
蒙脱土负载
氯化锌
喹喔啉衍生物
loaded montmoriUonite
zinc chloride
quinoxaline derivatives
