摘要
目的探讨高龄妊娠孕妇发生宫内死胎的原因。方法本研究采用回顾性研究方法对2009年1月1日至2014年12月31日因宫内死胎（单胎）在广州医科大学附属第三医院妇产科住院治疗的339例患者临床资料进行分析,根据孕妇分娩年龄分为高龄组（≥35岁）和非高龄组（20-34岁）,比较两组孕妇宫内死胎的原因。采用独立样本t检验、χ^2检验或Fisher精确概率法对数据进行统计学分析。结果高龄妊娠宫内死胎率为1.66%（61/3 670）比非高龄组1.10%（278/25 227）高,χ^2=8.670,P=0.003;两组宫内死胎各种病因发生率的比较,差异均无统计学意义（P均〉0.05）;高龄组不明原因宫内死胎发生率27.87%（17/61）明显比非高龄组7.55%（21/278）高,χ^2=20.74,P=0.000）。结论高龄妊娠孕妇发生宫内死胎风险比非高龄者高,需加强对高龄妊娠人群孕期母胎监测。
Objective To explore the causes of intrauterine fetal death in pregnancy women with advanced age. Methods Clinical data of 339 intrauterine fetal deaths （single fetus） were retrospectively analyzed. The patients were admitted to the obstetrics and gynecology department at The Third Affiliated Hospital of Guangzhou Medical University from January 1, 2009 to December 31, 2014. According to the age of pregnant woman at deliver, the cases were divided into advanced age group （≥ 35 years ） or and non-advanced age group （20 - 34 years）. The causes of intrauterine fetal deaths were compared between the two groups. Independent sample t test, Chi-square test or Fisher＇s exact test were used for statistical analysis. Results The incidence of intrauterine fetal death was higher in advanced age group when compared with non-advanced age group [ 1.66% （61/3 670） vs. 1.10% （278/25 227）, Z2 = 8. 670, P = 0. 003 ]. There were no significant differences of maternal complications incidences between the two groups （ all P vales more than 0. 05 ）. The rates of unknown factors of intrauterine fetal death in advanced age group and non-advanced age group were [27.87% （ 17/61 ） and 7.55% （21/278） respectively, χ^2 = 20. 74, P = 0. 000 ]. Conclusion Pregnancy women with advanced age present a higher risk of intrauterine fetal death than the non-advanced ones, so strengthen the maternal-fetal monitoring of pregnancy women with advanced age.
作者
龚景进
李晓梅
李思慧
李秀英
陈敦金
Gong Jinyjin Li Xiaomei Li Sihui Li Xiuying Chen Dunjin.(Department of Obstetrics and Gynecology, The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical Center for Critical Pregnant Women, Guangzhou 510150, China)
出处
《中华产科急救电子杂志》
2016年第3期178-181,共4页
Chinese Journal of Obstetric Emergency（Electronic Edition）
基金
广州市教育局协同创新重大项目(13xt04)
广州市科技惠民专项项目(2014Y2-00182)
产科重大疾病防控创新团队(2015KCXTD020)
关键词
母亲年龄
死胎
危险因素
Maternal age
Fetal death
Risk factors
