摘要
目的观察中药参芪七味饮对早中期慢性肾功能不全脾虚湿热证的临床疗效。方法收集符合纳入标准的病例96例,将入选病例在饮食营养、控制血压、控制血脂等基础治疗的基础上分为治疗组(替米沙坦+参芪七味饮)48例、对照组(替米沙坦)48例,疗程均为2个月。观察治疗前后24 h尿蛋白定量、血尿素氮、血肌酐及血超敏C反应蛋白,比较两组间的疗效差异。结果治疗组能降低CKD2-3期患者血尿素氮、血肌酐,降低蛋白尿(P<0.01),能降低超敏C反应蛋白(P<0.05),优于对照组。结论参芪七味饮能显著减少CKD2-3期脾虚湿热型患者的蛋白尿,改善肾功能,降低血超敏C反应蛋白,改善微炎症状态。
Objective To observe the clinical effect of Chinese medicine Shenqi Qiwei drink in teating chronic renal insufficiency in the early and middle stage which is the syndrome related to spleen deficiency and damping-heat in TCM. Methods 96 cases of patients were collected for inclusion criteria, and were randomly divided into treatment group（Telmisartan and Shenqi Qiwei drink） of48 patients and control group（Telmisartan） of 48 patients on the basis of dietary nutrition, control blood pressure and blood lipids and other basic treatment, with a course of two months. The changes of 24 h UPro, BUN, Scr and hs-CRP were observed before and after treatment in two groups. Results In the treatment group, the Scr and BUN and 24 h UPro reduced（ P〈0.01）, hs-CRP reduced（P〈0.05）, which were better than those of the control group. Conclusion Shenqi Qiwei drink can significantly reduce proteinuria of the patients with chronic renal insufficiency in the early and middle stage which is the syndrome related to spleen deficiency and damping-heat in TCM, protect renal, reduce hs-CRP, and improve microinflammatory state.
作者
阳贵林
章新宇
陈丹
YANG Guilin ZHANG Xinyu CHEN Dan(Department of Traditional Chinese Medicine, Pingxiang Mining Bureau General Hospital, Jiangxi Provine, Pingxiang 337000, China Department ofNephrology, Luxi County People＇s Hospital, Jiangxi Provine, Pingxiang 337000, China)
出处
《中国中医药现代远程教育》
2017年第2期82-84,共3页
Chinese Medicine Modern Distance Education of China
基金
江西省卫生计生委中医药科研基金【No:2014A165】
关键词
慢性肾功能不全
参芪七味饮
脾虚湿热
血肌酐
蛋白尿
微炎症状态
水肿
chronic renal insufficiency
Shenqi Qiwei drink
spleen deficiency and damping-heat
serum creatinine
proteinuria
microinflammatory state
edema
