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奥美拉唑静滴用于小儿上消化道出血治疗的临床效果观察 被引量:3

Clinical Observation of Omeprazole Infusion in Treatment of Upper Gastrointestinal Hemorrhage in Children
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摘要 目的:探讨分析奥美拉唑静滴用于小儿上消化道出血治疗的临床效果。方法:选取2014年1月-2016年1月在本院接受治疗的上消化道出血患儿80例作为研究对象,按照治疗方法的不同将其分为奥美拉唑组以及西咪替丁组,每组40例。西咪替丁组给予西咪替丁治疗,奥美拉唑组给予奥美拉唑治疗,试验结束后对比分析两组患儿的治疗效果、止血时间、呕吐咖啡样物或鲜血停止时间、隐血试验转阴时间、临床症状改善时间、住院时间以及不良反应发生率。结果:经过对比发现,奥美拉唑组患儿的治疗效果、止血时间、呕吐咖啡样物或鲜血停止时间、隐血试验转阴时间、临床症状改善时间、住院时间以及不良反应发生率与西咪替丁组比较差异均有统计学意义(P<0.05)。结论:相对于西咪替丁来说,奥美拉唑静滴治疗小儿上消化道出血疗效显著,安全性较高,不良反应较少,值得临床推广应用。 Objective: To investigate the clinical effect of Omeprazole infusion in the treatment of upper gastrointestinal bleeding in children.Method: Eighty patients with upper gastrointestinal bleeding treated in our hospital from January 2014 to January 2016 were divided into Omeprazole group and Cimetidine group according to the different treatment methods, 40 cases in each group, Cimetidine group was given Cimetidine treatment,Omeprazole group was given Omeprazole treatment.After experiment, the bleeding time, vomiting coffee-like or blood stop time, occult blood test negative time, clinical symptoms improved time, length of hospital stay and adverse reaction rates of two groups were compared.Result: In Omeprazole group, the treatment effect, hemostasis time, vomiting caffee-like or blood stopping time, occult blood test negative time, clinical symptom improvement time, hospitalization time and adverse reaction rate were better than Cimetidine group, the differences were statistically significant (P〈0.05) .Conclusion: Compared with Cimetidine, Omeprazole intravenous infusion in the treatment of upper gastrointestinal bleeding in children has significant efficacy, safety and less adverse reactions, it is worthy of clinical application.
作者 邹扬军 ZOU Yang-jun(Nankang District Traditional Chinese Medicine Hospital of Ganzhou, Ganzhou 341400, China)
出处 《中国医学创新》 CAS 2017年第7期69-72,共4页 Medical Innovation of China
关键词 奥美拉唑 小儿上消化道出血 临床效果 Omeprazole Upper gastrointestinal bleeding in children Clinical effect
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