期刊文献+

角膜新生血管治疗的研究现状 被引量:3

The current research status of the corneal neovascularization treatment
原文传递
导出
摘要 角膜新生血管是导致视力严重下降甚至致盲的重要病理性改变。随着细胞分子生物学、免疫学及药理学研究方法的进展,治疗角膜新生血管的方法不断取得突破。目前,临床常用的治疗方法包括糖皮质激素类药物、抗血管内皮生长因子、结膜移植、光动力疗法等。但尚无特效疗法。防治角膜新生血管发生是眼科领域研究的重点。 Corneal neovascularization(CNV) is one of the important pathological changes that leads to serious vision decline or even blindness. In recent years, with the deep study of molecular biology, immunology and pharmacology, the methods of treating CNV have made a breakthrough. At present, the common treatment methods include hormone drugs, anti-vascular endothelial growth factor, conjunctival transplantation, photodynamic therapy and so on. However, there is no effective therapeutic medicine or cure methods for CNV. How to prevent and treat CNV has become a hotspot in research in ophthalmology.
作者 温舒 杨炜 WEN Shu YANG Wei(Department of Ophthalmology, First Hospital Affiliated to Shihezi University, Shihezi Xinjiang Uygur Autonomous Region 832000, Chin)
出处 《国际眼科纵览》 2017年第1期43-47,共5页 International Review of Ophthalmology
关键词 角膜新生血管 骨髓间充质干细胞 氢气 corneal neovascularization hone mesenchymal stem cells hydrogen
  • 相关文献

参考文献3

二级参考文献55

  • 1Ayhan Dursun,Mustafa Kemal Arici,Feyza Dursun,Ayse Vural Ozec,Mustafa Ilker Toker,Haydar Erdogan,Aysen Topalkara.Comparison of the effects of bevacizumab and ranibizumab injection on corneal angiogenesis in an alkali burn induced model[J].International Journal of Ophthalmology(English edition),2012,5(4):448-451. 被引量:10
  • 2Kenyon B M.A model of angiogenesis in the mouse cornea,1996(08).
  • 3Fang Lu,Ron A. Adelman.Are intravitreal bevacizumab and ranibizumab effective in a rat model of choroidal neovascularization?[J]. Graefe’s Archive for Clinical and Experimental Ophthalmology . 2009 (2)
  • 4Chang J H,Gabison E E,Kato T,et al.Corneal neovascularization. Current Opinion in Ophthalmology . 2001
  • 5Lee P,Wang CC,Adamis AP.Ocular neovascularization: an epidemiologic review. Survey of Ophthalmology . 1998
  • 6You IC,Kang IS,Lee SH, et al.Therapeutic effect of subconjunctival injection of bevacizumab in the treatment of corneal neovascularization. Acta Ophthalmologica Scandinavica . 2009
  • 7Neufeld G,Cohen T,Gengrinovitch S,et al.Vascular endothelial growth factor (VEGF) and its receptor. FASEB Journal,The . 1999
  • 8Kerbel R,Folkman J.Clinical translation of angiogenesis inhibitors. Nature Reviews Cancer . 2002
  • 9Dana MR,Streilein JW.Loss and restoration of immune privilege in eyes with corneal neovascularization. Investigative Ophthalmology . 1996
  • 10Phillips GD,Stone AM,Jones BD,et al.Vascular endothelial growth factor (rhVEGF165) stimulates direct angiogenesis in the rabbit cornea. In Vivo . 1994

共引文献21

同被引文献50

引证文献3

二级引证文献4

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部