摘要
目的观察MEBT/MEBO(moist exposed burn therapy/moist exposed burn ointment,原位再生医疗技术)治疗老年WagnerⅢ级糖尿病足的临床疗效。方法将2014年6月—2016年2月广西中医药大学第一附属医院和右江民族医学院附属医院收治的52例老年WagnerⅢ级糖尿病足患者随机分为MEBO(moist exposed burn ointment,湿润烧伤膏)组(27例)和rb-bFGF(重组牛碱性成纤维细胞生长因子)组(25例)。MEBO组患者创面外涂MEBO治疗,rb-bFGF组患者创面外涂rb-bFGF凝胶治疗,于治疗60 d后对比两组患者创面治疗效果及治疗前后伴随症状评分差值。结果治疗60 d后,MEBO组患者创面明显缩小,疼痛、麻木等症状明显缓解,疗效优于rb-bFGF组,P<0.05,差异具有统计学意义。结论 MEBT/MEBO能够有效促进老年WagnerⅢ级糖尿病足创面的愈合,缓解创面疼痛、麻木等临床症状,改善患者生活质量,值得临床推广应用。
Objective To observe the clinical efficacy of Moist Exposed Burn Therapy/Moist Exposed Burn Ointment（MEBT/MEBO） in the treatment of Wagner grade Ⅲ diabetic foot（DF） in the elderly people.Methods A total of52 elderly patients with Wagner grade Ⅲ diabetic foot admitted to The First Affiliated Hospital of Guangxi University of Chinese Medicine and The Affiliated Hospital of Youjiang Medical College for Nationalities between June 2014 and February2016 were randomly divided into MEBO group（27 patients） and rb-bFGF group（25 patients）.Patients in MEBO group were treated with the external application of MEBO while patients in rb-bFGF group were treated with the external application of rb-bFGF gel.The clinical efficacy and the score differences of concomitant symptoms before and after the treatment between the two groups were compared on day 60 of the treatment.Results On day 60 of the treatment,the wound size was obviously decreased and the symptoms such as pain and numbness were remarkably relieved in MEBO group,which was superior to that in the rb-bFGF group,with statistically significant difference（P〈0.05）.Conclusion MEBT/MEBO deserves to be promoted in clinical treatment of Wagner grade Ⅲ diabetic foot in the elderly population since it is effective in promoting the wound healing and relieving symptoms such as pain and numbness and improving patients＇ quality of life.
出处
《中国烧伤创疡杂志》
2017年第1期44-47,共4页
The Chinese Journal of Burns Wounds & Surface Ulcers
基金
2014年广西科学研究与技术开发计划项目(项目编号:桂科攻14124004-1-2)
2014年广西自然科学基金面上项目(2014GXNSFAA118135)~~
