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精准医学和中医药创新发展 被引量:29

Precision Medicine and Innovative Development of Traditional Chinese Medicine(TCM)
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摘要 精准医学应用现代遗传技术、分子影像技术、生物信息技术,结合患者临床和个体信息,实行精准的风险预测和精准的疾病分类、诊断及治疗,制定具有个性化的疾病预防和治疗方案,以实现疗效精准评估、预后的精准判断为目标,现已成为当代医学发展的一个热点方向。本文对精准医学发展的背景、内涵、发展状况及其影响作了简要介绍。中医学的整体观、以人为本、辨证论治等基本理念和诊疗模式,彰显了同病异治、因人而异、因病程而异的个性化治疗的追求,与精准医学的要求高度契合。加强中医药的精准医学研究,是推动中医药创新发展的重要动力。为此要努力挖掘和弘扬中医药自身固有的精准医学特色和优势;探索在当代条件下传承和发展中医药精准医学和个性化治疗的思路、技术和方法;丰富中医药精准治疗的实践模式。在中医药精准医学的研究中,需要以"精准诊断"、"精准治疗"两大问题为切入点,坚持突出中医药个性化、动态化、整体性诊疗理念,推动中医药的创新发展。 Precision medicine was recognized as a research focus nowadays as it shows the promise of overcoming the challenge of health and medicine that we are currently facing. Combining novel techniques in genetics, molecular imaging and bioinformatics with clinical and personal information, precision medicine can make sound health risk prediction and accurate classification, diagnosis and therapy to establish personalized disease prevention and treatment programs and to achieve accurate assessment of individual therapy and prognosis. This paper briefly summarized the background information, scientific content, current development and potential effect of precision medicine on modern medical science. The essence of traditional Chinese medicine(TCM), which is body-oriented entirety diagnosis and treatment based on syndrome differentiation, highly matched the core notion of precision medicine, emphasizing different treatments for different people with the same disease at different stages. Therefore, further investigation of TCM with the idea of precision medicine will definitely promote its innovative development. Thus, it is important that we profoundly mine and enlarge the recognized vantages of TCM, explore new strategies, technologies and methodologies to inherit and promote precision medicine and personalized therapy in TCM; and enrich the ways of the approaches of TCM precision therapy. Taking "precision diagnosis" and "precision therapy" as our focuses, we will afford to promote TCM by emphasizing its philosophy of personalized, dynamic and entirety diagnoses and treatment.
作者 陈凯先
出处 《世界科学技术-中医药现代化》 CSCD 2017年第1期7-18,共12页 Modernization of Traditional Chinese Medicine and Materia Medica-World Science and Technology
关键词 精准医学 中医药 创新发展 Precision medicine traditional Chinese medicine innovative development
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