摘要
In recent years, the whole life science community has witnessed the advance and breakthrough in the genome editing technologies, including zinc-finger nucleases （ZFNs）, transcription activator-like effector （TALE） nucleases （TALENs） and clustered, regularly interspaced, short palindromic repeats （CRISPR）-CRISPR-associated （Cas） systems （CRISPR/Cas9） [1-3]. With these tools, scientists are able to introduce site-specific modifications in the genome of a wide range of organisms from invertebrates to vertebrates.
SPECIAL TOPIC:Fish Genome Editing In recent years,the whole life science community has witnessed the advance and breakthrough in the genome editing technologies,including zinc-finger nucleases(ZFNs),transcription activator-like effector(TALE)nucleases(TALENs)and clustered,regularly interspaced,short palindromic repeats(CRISPR)–CRISPR-associated(Cas)systems(CRISPR/Cas9)[1–3].With these tools。
