摘要
目的探讨晚期早产儿(LPI)早期智能发育结局。方法选择2012年1月至2015年1月新生儿病房收治的出生胎龄34~36+6周、治愈出院并定期规律随访的106例早产儿为晚期早产儿组;随机抽取同期120例健康足月儿(FPI)为对照组。对校正年龄40周的晚期早产儿及40周龄的足月儿进行新生儿神经行为测定(NBNA),晚期早产儿校正龄3、6、12月龄或者足月儿3、6、12月龄时采用Gesell发育量表进行评估。结果 LPI组NBNA评分低于37分,低于FTI组(P<0.05)。校正龄3月龄时,LPI组大运动、精细运动、个人社交落后于FTI组(P<0.05);校正龄6月龄时,LPI组适应性、大运动、精细运动落后于FTI组(P<0.05);校正年龄12月龄时,LPI组适应性、大运动、个人社交测评明显低于FTI组(P<0.05)。结论晚期早产儿早期智能发育迟缓,需加强神经发育监测。
Objective To investigate the early intellectual developmental outcome of late preterm infants. Methods A total of 106 late preterm infants with a gestational age of 34-36^＋6 weeks who were admitted to the neonatal ward between January 2012 and January 2015, cured, discharged, and regularly followed up at the outpatient service for high-risk children were enrolled as the preterm group. A total of 120 healthy full-term infants during the same period were randomly selected as the term group. Neonatal behavioral neurological assessment（NBNA） was performed for late preterm infants at a corrected gestational age of 40 weeks and full-term infants at a gestational age of 40 weeks. The Gesell Developmental Scale was used for late preterm infants at a corrected age of 3, 6, and 12 months and full-term infants at an age of 3, 6, and 12 months. Results The preterm group had an NBNA score of 37 and a significantly lower NBNA score than the term group（P〈0.05）. At the corrected age of 3 months, the preterm group had significantly lower scores of gross motor, fine motor, and social competence than the term group（P〈0.05）. At the corrected age of 6 months, the preterm group had significantly lower scores of adaptability, gross motor, and fine motor than the term group（P〈0.05）. At the corrected age of 12 months, the preterm group had significantly lower scores of adaptability, gross motor, and social competence than the term group（P〈0.05）. Conclusions Late preterm infants have early intellectual developmental delay. It is necessary to perform neurodevelopmental monitoring for late preterm infants.
出处
《中国当代儿科杂志》
CAS
CSCD
北大核心
2017年第2期142-146,共5页
Chinese Journal of Contemporary Pediatrics
基金
广东省科技厅科技计划项目(2012B061700010)
关键词
智能发育
随访
晚期早产儿
Intellectual development
Follow-up
Late preterm infant
