摘要
富血小板血浆(PRP)是将新鲜全血通过特定离心方式得到的含高浓度血小板的血浆,是1种血小板浓缩物。现已知PRP富含多种生长因子,是自体生长因子库。作为自体血液成分,PRP输注在临床辅助治疗方法中,与其他重组生长因子或干细胞疗法相比更安全、更实际。目前PRP已广泛用于整形外科、口腔颌面外科及难愈合伤口和骨缺损的修复。但关于PRP中主要生长因子的作用、血小板的有效含量及最佳浓度和PRP中白细胞的临床效应等问题,至今并不完全明确,本文将对PRP中的主要成分及作用的最新研究进展做一综述,为富血小板血浆的标准化制备及临床应用现状做一理论总结。
Platelet rich plasma is a kind of platelet concentrate, which is obtained by means of a certain centrifugal method which can accumulate a high concentration of platelet. Platelet rich plasma is known to be an autologous growth factor library, which is rich in many kinds of growth factors. Platelet rich plasma used as an autologous component is safer and more practical compared with other recombinant growth factor or stem cell in clinical adjuvant therapy. Platelet rich plasma has been widely used in plastic surgery, oral and maxillofacial surgery, the repair of wound healing and bone defect. However, at present, the main growth factors＇ effect, the effective content and the best concentration of platelet and the clinical effect of white blood cell in platelet rich plasma are not completely clear. In this article, we will review the recent advances in the study of the main components of platelet rich plasma and their effects, and provide a theoretical basis for the preparation and clinical application of platelet rich plasma.
出处
《中国输血杂志》
CAS
北大核心
2016年第12期1408-1412,共5页
Chinese Journal of Blood Transfusion
基金
吉林省卫生计生委项目(20152004)
