摘要
目的:设计一种新型体模,既能根据实际条件测量鼻咽癌放疗剂量,又能同时测量图像几何畸变度。方法:采用对放疗剂量极其敏感的热释光材料,构建头颈部U型槽作为载体,模拟病人实际头颈部肿瘤的大小轮廓、解剖结构和位置,将各个小组件组装拼接,构建新型头颈部放疗剂量测量体模,实现鼻咽癌放疗剂量测量;采用该新型测量模型,将同种形状模块按照一定规律排列和变化,测量图像三维几何畸变度。结果:与传统鼻咽癌放疗剂量的测量体模相比,新型体模能够根据病人实际条件进行精确调整,精确测量病人实际受照射剂量;与传统图像几何畸变度体模相比,新型体模能提供更多新型测量模型和排列方式来测量畸变度,显著提高测量精度。结论:新型体模将剂量测量体模和畸变度测量体模有机结合,既能准确测量鼻咽癌放疗剂量,又能精确测量几何畸变度,简单实用,在临床实际应用有很好的推广价值。
Objective To design a new phantom for measuring the radiotherapy dose and geometric distortion for nasopharyngeal carcinoma（NPC）. Methods A thermoluminescence material highly sensitive to radiotherapy dose was used to prepare a U-shaped cast of the head and neck that simulated the size, profile, anatomical structure, and location of the head and neck tumors of patients. The components were assembled into a phantom for measurement of the radiotherapy dosimetry on the head and neck and in the NPC loci. Using this phantom, the three- dimensional geometric distortion was measured after adjustments of the modules. Results Compared with the conventional phantom for measuring radiotherapy dose for NPC, this new phantom allowed precise adaptive adjustment for individual patients for accurate dose measurement. Compared with the conventional phantom for measuring geometric distortion, this phantom provided more models and more variable arrangements for measurement of the distortion degree to improve the measurement accuracy. Conclusion The new phantom that integrates the conventional dosimetry phantom and distortion measurement phantom can achieve more accurate and convenient measurement of radiotherapy dose and geometric distortion in NPC patients.
作者
朱远湖
王学涛
戴振晖
张白霖
招什武
杨耕
朱琳
蔡春雅
李飞
陈超敏
ZHU Yuanhu WANG Xuetao DAI Zhenhui ZHANG Bailin ZHAO Shiwu YANG Geng ZHU Lin CA/Chunya LI Fei CHEN Chaomin(Department of Radiotherapy, Guangdong Hospital of Traditional Chinese Medicine, Guangzhou 510006, China School of Biomedical Engineering, Southern Medical University, Guangzhou 510515, China)
出处
《中国医学物理学杂志》
CSCD
2017年第1期13-16,共4页
Chinese Journal of Medical Physics
基金
广东省科技计划项目(2015A020214013)
关键词
鼻咽癌
放疗剂量
几何畸变度
体模
nasopharyngeal carcinoma
radiotherapy dose
geometric distortion
phantom
