摘要
目的:观察逍遥散加减方联合西药治疗糖尿病合并反复泌尿系统感染的临床疗效。方法:选择86例肝郁脾虚型糖尿病合并反复泌尿系统感染患者,随机分为观察组与对照组各43例。对照组予血糖控制治疗,同时给予常规抗感染、碱化尿液治疗。观察组在对照组治疗基础上予逍遥散加减方治疗,2组均治疗14天。对2组临床疗效、尿菌转阴时间、复发情况以及治疗前后的血糖情况进行比较。结果:观察组总有效率90.70%,对照组总有效率79.07%,2组比较,差异有统计学意义(P<0.05)。治疗后,2组空腹血糖与餐后2 h血糖均较治疗前降低(P<0.05),但2组比较,差异无统计学意义(P>0.05)。观察组0~7天和超过14天的尿菌转阴率与对照组比较,差异均有统计学意义(P<0.05)。观察组平均尿菌转阴时间短于对照组,差异均有统计学意义(P<0.05)。2组1月内复发率无统计学差异(P>0.05);观察组6月内复发率低于对照组,差异有统计学意义(P<0.05)。结论:逍遥散加减方对于糖尿病合并反复发作的泌尿系统感染具有良好的治疗作用,与常规西药联合使用,既能够提高疗效,又能够缩短尿菌转阴时间,提高转阴率,还能够有效降低感染的复发率。
Objective： To observe the clinical effect of modified Xiaoyaosan prescription combined with western medicine in treating diabetes complicated with recurrent urinary system infection. Methods： Selected 86 cases of patients with diabetes of liver stagnation and spleen deficiency syndrome type complicated with recurrent urinary system infection, and divided them into the observation group and the control group randomly, 43 cases in each group. Both groups were treated with blood glucose control,and at the same time received the treatment of anti-infection and alkalization of urine. The observation group was additionally treated with modified Xiaoyaosan prescription. Two groups were both treated for 14 days. Compared the clinical effect,the negative conversion time of urine bacteria,recurrence and blood glucose before and after treatment in two groups. Results： The total effective rate was 90.70% in the observation group and 79.07% in the control group, the significant difference being found in the comparison between two groups（P 〈 0.05）. After treatment,blood glucose in fasting condition and blood glucose 2 hours after meal in both groups were lower than those before treatment（P 〈 0.05）, but no significant difference was found in the comparison of the two groups（P 〉 0.05）. While 0~7 days and over 14 days,compared the negative conversion time of urine bacteria of the observation group with that of the control group, the difference was significant（P 〈 0.05）. The mean negative conversion time of urine bacteria of the observation group was shorter than that of the control group（P 〈 0.05）. The recurrence rate in two groups within one month showed no significance in the difference（P 〉 0.05）. But compared the recurrence rate in two groups within six month, the recurrence rate of the observation group was lower than that of the control group. Conclusion： The therapy of modified Xiaoyaosan prescription combined with western medicine for diabetes complicated with recurrent urinary system infection has good curative function. When combined with western medicine, it can enhance the curative effect, shorten the negative conversion time of urine bacteria,increase negative rate and effectively reduce the recurrence rate of infection.
出处
《新中医》
CAS
2017年第2期60-62,共3页
New Chinese Medicine
关键词
糖尿病
泌尿系统感染
肝郁脾虚证
中西医结合疗法
逍遥散
Diabetes
Urinary system infection
Liver stagnation and spleen deficiency type
Integrated Chinese and western medicine therapy
Xiaoyao san
